Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis

Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis

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http://www.wikidata.org/entity/Q28185488

Q28185488

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Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues Human genetic disorders and knockout mice deficient in glycosaminoglycan Chondroitin 4-O-sulfotransferase-1 regulates the chain length of chondroitin sulfate in co-operation with chondroitin N-acetylgalactosaminyltransferase-2 Regulation of the chondroitin/dermatan fine structure by transforming growth factor-beta1 through effects on polymer-modifying enzymes.Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.Development of a mouse monoclonal antibody against the chondroitin sulfate-protein linkage region derived from shark cartilage.Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders.Metabolism of cartilage proteoglycans in health and disease Involvement of human natural killer-1 (HNK-1) sulfotransferase in the biosynthesis of the GlcUA(3-O-sulfate)-Gal-Gal-Xyl tetrasaccharide found in α-thrombomodulin from human urine.Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome.Protein-protein interaction analysis highlights additional loci of interest for multiple sclerosis.Chondroitin sulfate/dermatan sulfate hybrid chains in the development of cerebellum. Spatiotemporal regulation of the expression of critical disulfated disaccharides by specific sulfotransferases.Specific genes involved in synthesis and editing of heparan sulfate proteoglycans show altered expression patterns in breast cancer CHST11 gene expression and DNA methylation in breast cancer GlcUAβ1-3Galβ1-3Galβ1-4Xyl(2-O-phosphate) is the preferred substrate for chondroitin N-acetylgalactosaminyltransferase-1.Highlights of glycosylation and adhesion related genes involved in myogenesis.Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells.Dermatan sulfate is involved in the tumorigenic properties of esophagus squamous cell carcinoma.Deciphering the Mode of Action of the Processive Polysaccharide Modifying Enzyme Dermatan Sulfate Epimerase 1 by Hydrogen-Deuterium Exchange Mass Spectrometry.Chondroitin sulfate "wobble motifs" modulate maintenance and differentiation of neural stem cells and their progeny.Human genetic disorders caused by mutations in genes encoding biosynthetic enzymes for sulfated glycosaminoglycans Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate.Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: insights into the sugar sequences with bioactivities.CHST11/13 Regulate the Metastasis and Chemosensitivity of Human Hepatocellular Carcinoma Cells Via Mitogen-Activated Protein Kinase Pathway.Chondroitin 4-O-Sulfotransferase Is Indispensable for Sulfation of Chondroitin and Plays an Important Role in Maintaining Normal Life Span and Oxidative Stress Responses in Nematodes.Chondroitin 4-O-sulfotransferase-2 regulates the number of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1.Two dermatan sulfate epimerases form iduronic acid domains in dermatan sulfate.Prognostic impact of chondroitin-4-sulfotransferase CHST11 in ovarian cancer.N-linked oligosaccharides on chondroitin 6-sulfotransferase-1 are required for production of the active enzyme, Golgi localization, and sulfotransferase activity toward keratan sulfate.Expression of chondroitin-4-O-sulfotransferase in Escherichia coli and Pichia pastoris.Functions of chondroitin sulfate/dermatan sulfate chains in brain development. Critical roles of E and iE disaccharide units recognized by a single chain antibody GD3G7.Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency.Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain.CHST14/D4ST1 deficiency: New form of Ehlers-Danlos syndrome.Extrahepatic Drug-Metabolizing Enzymes and Their Significance Extracellular matrix and platelet function in patients with musculocontractural Ehlers-Danlos syndrome caused by mutations in theCHST14gene

P2860

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P2860

Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis

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http://www.wikidata.org/entity/Q28185488

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2003 nî lūn-bûn

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2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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