PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
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CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motilityG protein-coupled receptor kinase 2 positively regulates epithelial cell migrationThe MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.Phosphorylation of actopaxin regulates cell spreading and migrationRACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motilityUp-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells.Critical role of actin-associated proteins in smooth muscle contraction, cell proliferation, airway hyperresponsiveness and airway remodelingSmall molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domain.Negative feedback regulation of the ERK1/2 MAPK pathwayBRAF activates and physically interacts with PAK to regulate cell motilityExtracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexinPAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesisAdhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylationGoverning epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosisFocal adhesion kinase: in command and control of cell motilityFAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassemblyMitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion.Identification of phosphorylation sites in betaPIX and PAK1Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transportExtracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate modelFocal adhesion kinase as a regulator of cell tension in the progression of cancer.NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations.MEK1 activation by PAK: a novel mechanism.Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDISynthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.Integrins as Therapeutic Targets for Respiratory DiseasesEpidermal Growth Factor Receptor Cell Proliferation Signaling Pathwaysp21-Activated kinases are required for transformation in a cell-based model of neurofibromatosis type 2.Cadherins and Pak1 control contact inhibition of proliferation by Pak1-betaPIX-GIT complex-dependent regulation of cell-matrix signaling.Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.Differences in integrin expression and signaling within human breast cancer cells.In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors.Potential compensation among group I PAK members in hindlimb ischemia and wound healing.Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation.Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retractionGroup I Paks as therapeutic targets in NF2-deficient meningioma.P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells.
P2860
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P2860
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@ast
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@en
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@nl
type
label
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@ast
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@en
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@nl
prefLabel
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@ast
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@en
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@nl
P2093
P2860
P3181
P356
P1476
PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
@en
P2093
Adel Tarcsafalvi
Andrew D Catling
H Bruce Diaz
J Thomas Parsons
Jill K Slack-Davis
Maja Zecevic
Mark S Marshall
Michael J Weber
Scott A Boerner
Scott T Eblen
P2860
P304
P3181
P356
10.1083/JCB.200212141
P407
P577
2003-07-01T00:00:00Z