Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat
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The apoptotic signaling pathway activated by Toll-like receptor-2Facts and fiction: the impact of hypothermia on molecular mechanisms following major challengeUpdate on Inflammatory Biomarkers and Treatments in Ischemic StrokeInflammation and infection in clinical strokeEfficient discovery of anti-inflammatory small-molecule combinations using evolutionary computingCentral and haematopoietic interleukin-1 both contribute to ischaemic brain injury in miceEffect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time windowHIV-1 coat protein gp120 stimulates interleukin-1beta secretion from human neuroblastoma cells: evidence for a role in the mechanism of cell deathMicroglia-derived proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta induce Purkinje neuronal apoptosis via their receptors in hypoxic neonatal rat brainBroken or maladaptive? Altered trajectories in neuroinflammation and behavior after early life adversityRole of nitric oxide in the cerebrovascular and thermoregulatory response to interleukin-1 beta.Recombinant human interleukin-1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial.Caspases as treatment targets in stroke and neurodegenerative diseases.Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemiaInfection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome.Matrix remodeling after stroke. De novo expression of matrix proteins and integrin receptors.Apoptosis and necrosis in cerebrovascular disease.Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity.The acute phase response and soman-induced status epilepticus: temporal, regional and cellular changes in rat brain cytokine concentrations.The neuroimmune-endocrine axis: pathophysiological implications for the central nervous system cytokines and hypothalamus-pituitary-adrenal hormone dynamics.Therapeutic potential of anti-inflammatory drugs in focal stroke.Stroke genomics: approaches to identify, validate, and understand ischemic stroke gene expression.The blood-brain barrier in health and disease.Interleukin (IL) 1beta, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implicationsCombined deficiency of IL-1beta18, but not IL-1alphabeta, reduces susceptibility to hypoxia-ischemia in the immature brain.Potential of anticytokine therapies in central nervous system ischaemia.Astrogliosis is delayed in type 1 interleukin-1 receptor-null mice following a penetrating brain injury.IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient miceThe role of astroglia in neuroprotectionIntrathecal inflammation precedes development of Alzheimer's diseaseTransplacental murine cytomegalovirus infection in the brain of SCID miceInterleukin-1β in Central Nervous System Injury and Repair.Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage.New horizons for primary intracerebral hemorrhage treatment: experience from preclinical studies.Caspase inhibitors as neuroprotective agents.Interleukin-1 and neuronal injury.A novel hypothesis-unbiased method for Gene Ontology enrichment based on transcriptome data.Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury.Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage.IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults.
P2860
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P2860
Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@ast
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@en
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@nl
type
label
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@ast
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@en
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@nl
prefLabel
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@ast
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@en
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@nl
P3181
P1476
Interleukin-1 receptor antagon ...... xic neuronal damage in the rat
@en
P2093
J K Relton
N J Rothwell
P3181
P356
10.1016/0361-9230(92)90033-T
P407
P577
1992-08-01T00:00:00Z