about
Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk.RET germline mutations identified by exome sequencing in a Chinese multiple endocrine neoplasia type 2A/familial medullary thyroid carcinoma familyMain roads to melanomaCombined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcomaImmunoaffinity profiling of tyrosine phosphorylation in cancer cellsMutational activation of the MAP3K8 protooncogene in lung cancerTyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signalingRegulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblastsUse of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisRegulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stressDynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA)Trafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domainThe unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1Mediation of the DCC apoptotic signal by DIP13 alphaIdentification of STAT3 as a substrate of receptor protein tyrosine phosphatase TRegulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibitionAn activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cellsP38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcriptionTSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulationShepherding AKT and androgen receptor by Ack1 tyrosine kinaseTumor-derived extracellular mutations of PTPRT /PTPrho are defective in cell adhesionAllosteric activation of the protein kinase PDK1 with low molecular weight compoundsBrk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinPseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptorIdentification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cellsPhospho-tyrosine dependent protein-protein interaction networkEpidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathwaysEGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinibCell signaling by receptor tyrosine kinasesOncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastomaTumour suppressor function of protein tyrosine phosphatase receptor-TThe role of protein tyrosine phosphatase 1B in Ras signalingPHLiPPing the switch on Akt and protein kinase C signalingTherapeutic Implications of Targeting AKT Signaling in MelanomaPtpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesisOn the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporineIdentification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor TSelectivity of docking sites in MAPK kinases
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Oncogenic kinase signalling
@ast
Oncogenic kinase signalling
@en
Oncogenic kinase signalling
@nl
type
label
Oncogenic kinase signalling
@ast
Oncogenic kinase signalling
@en
Oncogenic kinase signalling
@nl
prefLabel
Oncogenic kinase signalling
@ast
Oncogenic kinase signalling
@en
Oncogenic kinase signalling
@nl
P3181
P356
P1433
P1476
Oncogenic kinase signalling
@en
P2093
P Blume-Jensen
P2888
P304
P3181
P356
10.1038/35077225
P407
P577
2001-05-17T00:00:00Z
P5875
P6179
1037528958