IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway - Wikidata - awgldk - TriplyDB

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

http://www.wikidata.org/entity/Q28190704

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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1 Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression IRF7: activation, regulation, modification and function Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanisms Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5 Emerging roles for the non-canonical IKKs in cancer Viral apoptosis is induced by IRF-3-mediated activation of Bax A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter Activation of interferon regulatory factor 5 by site specific phosphorylation Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo Evasion of antiviral immunity through sequestering of TBK1/IKKε/IRF3 into viral inclusion bodies The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1 IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction WDFY1 mediates TLR3/4 signaling by recruiting TRIF The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response Endotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expres The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3 Mapping a dynamic innate immunity protein interaction network regulating type I interferon production A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling PPM1B negatively regulates antiviral response via dephosphorylating TBK1 Innate immune recognition of viral infection

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

http://www.wikidata.org/entity/Q28190704

description

2003 nî lūn-bûn

@nan

2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@ast

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@en

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@nl

type

label

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@ast

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@en

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@nl

prefLabel

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@ast

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@en

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@nl

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Nature Immunology

P1476

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

@en

P2093

Anthony J Coyle

http://www.w3.org/2001/XMLSchema#string

Daniel C Rowe

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Douglas T Golenbock

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Katherine A Fitzgerald

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Kerrie L Faia

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Sarah M McWhirter

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Sha-Mei Liao

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491-6

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scholarly article

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320318

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10.1038/NI921

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5

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4

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2003-05-01T00:00:00Z

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12692549

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