Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways
about
Niacin, an old drug with a new twistGPR109A and vascular inflammationPrimary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling networkAnti-inflammatory effects of nicotinic acid in human monocytes are mediated by GPR109A dependent mechanisms.A "hot" topic in dyslipidemia management--"how to beat a flush": optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention.Axonopathy is associated with complex axonal transport defects in a model of multiple sclerosis.Future of GPR109A agonists in the treatment of dyslipidaemia.The flavonoid luteolin inhibits niacin-induced flushNicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells.Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells.Gene set signature of reversal reaction type I in leprosy patients.Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed miceEffects of nicotinic acid on gene expression: potential mechanisms and implications for wanted and unwanted effects of the lipid-lowering drug.Extended release niacin-laropiprant in patients with hypercholesterolemia or mixed dyslipidemias improves clinical parametersEffect of Extended-Release Niacin/Laropiprant Combination on Plasma Adiponectin and Insulin Resistance in Chinese Patients with DyslipidaemiaOcular Effects of Niacin: A Review of the Literature.Nicotinic Acid Accelerates HDL Cholesteryl Ester Turnover in Obese Insulin-Resistant Dogs.Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.Nicotinic acid: an old drug with a promising futureThe importance of NAD in multiple sclerosisNiacin: a re-emerging pharmaceutical for the treatment of dyslipidaemia.Atherosclerosis regression and high-density lipoproteins.New evidence for nicotinic acid treatment to reduce atherosclerosis.Nicotinic acid-mediated activation of both membrane and nuclear receptors towards therapeutic glucocorticoid mimetics for treating multiple sclerosis.Phenylbutyrate induces apoptosis and lipid accumulations via a peroxisome proliferator-activated receptor gamma-dependent pathway.Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis.A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development.Action of nicotinic acid on the reversion of hypoxic-inflammatory link on 3T3-L1 adipocytes.Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells.Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects.Niacin: the only vitamin that reduces cardiovascular events.A transcriptomic study of myogenic differentiation under the overexpression of PPARγ by RNA-Seq.Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1.Cloning and characterization of the hamster and guinea pig nicotinic acid receptors.Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue.
P2860
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P2860
Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@ast
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en-gb
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@nl
type
label
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@ast
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en-gb
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@nl
prefLabel
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@ast
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en-gb
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@nl
P50
P3181
P1476
Niacin induces PPARgamma expre ...... ostaglandin synthesis pathways
@en
P2093
Robert H te Poele
Robert Te Poole
P304
P3181
P356
10.1016/J.BCP.2005.11.019
P407
P577
2006-02-28T00:00:00Z