Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study
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Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosaIn vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell linesAspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammationReview article: prevention of non-steroidal anti-inflammatory drug gastrointestinal complications--review and recommendations based on risk assessmentNitric oxide-modulating agents for gastrointestinal disordersPeptic ulcer disease todayPharmacologic profile and therapeutic potential of NCX 4016, a nitric oxide-releasing aspirin, for cardiovascular disordersTherapeutic effects of nitric oxide-aspirin hybrid drugsMechanism of action of novel NO-releasing furoxan derivatives of aspirin in human plateletsBuilding a better aspirin: gaseous solutions to a century-old problemEffect of antisecretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulantsRoles of platelet and endothelial cell COX-1 in hypercholesterolemia-induced microvascular dysfunctionNitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccinationComparison between 3-Nitrooxyphenyl acetylsalicylate (NO-ASA) and O2-(acetylsalicyloxymethyl)-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (NONO-ASA) as safe anti-inflammatory, analgesic, antipyretic, antioxidant prodrugs.Dendritic cell-based vaccines: barriers and opportunitiesPlatelets, atherosclerosis and the endothelium: new therapeutic targets?Reversibility of gastric mucosal lesions induced by sodium phosphate tablets and characterized by probe-based confocal laser endomicroscopyChemotherapeutic potential of diazeniumdiolate-based aspirin prodrugs in breast cancer.Wnt/β-Catenin Signaling Pathway in Skin Carcinogenesis and Therapy.Nitrate, bacteria and human health.Recent developments in nitric oxide donor drugs.NOSH-Aspirin: A Novel Nitric Oxide-Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals.Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential.Inhibition of pancreatic intraepithelial neoplasia progression to carcinoma by nitric oxide-releasing aspirin in p48(Cre/+)-LSL-Kras(G12D/+) miceLeukocyte infiltration in cancer creates an unfavorable environment for antitumor immune responses: a novel target for therapeutic intervention.Nitric oxide-donating aspirin inhibits beta-catenin/T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear beta-catenin-TCF association.Degradation of NF-κB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells.Development of novel agents based on nitric oxide for the control of colon cancer.Colon cancer and the elderly: from screening to treatment in management of GI disease in the elderly.Organic nitrate metabolism and action: toward a unifying hypothesis and the future-a dedication to Professor Leslie Z. Benet.NO-donating NSAIDs and cancer: an overview with a note on whether NO is required for their action.Treatment and chemoprevention of NSAID-associated gastrointestinal complications.Modulating endothelial nitric oxide synthase: a new cardiovascular therapeutic strategy.Gastrointestinal effects of aspirin.Therapeutic potential of new hydrogen sulfide-releasing hybrids.An overview of history, pathogenesis and treatment of perforated peptic ulcer disease with evaluation of prognostic scoring in adults.Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action.Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosa.Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety.
P2860
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P2860
Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study
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2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@ast
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@en
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@nl
type
label
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@ast
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@en
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@nl
prefLabel
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@ast
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@en
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@nl
P2093
P356
P1433
P1476
Gastrointestinal safety of NO- ...... of of concept endoscopic study
@en
P2093
Antonio Morelli
Luca Santucci
Paolo Gresele
Roberto Maffei Faccino
P356
10.1053/GAST.2003.50096
P407
P577
2003-03-01T00:00:00Z