The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
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TIF1gamma, a novel member of the transcriptional intermediary factor 1 familyMSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23)The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia geneSelf-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteinsCloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1.A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressorDivergent hTAFII31-binding motifs hidden in activation domainshuASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctionsAF15q14, a novel partner gene fused to the MLL gene in an acute myeloid leukaemia with a t(11;15)(q23;q14)Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cellsHepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcriptionLeukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionIdentification and characterization of the human Set1B histone H3-Lys4 methyltransferase complexSolution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferaseGenes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifsAcute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion productCloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemiaThe t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein familyLeucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemiaEWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft partsWHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myelomaAssociation of SET domain and myotubularin-related proteins modulates growth controlIdentification of FMR2, a novel gene associated with the FRAXE CCG repeat and CpG islandALL1 fusion proteins induce deregulation of EphA7 and ERK phosphorylation in human acute leukemiasMammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeresPanhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.The gene for glycogen-storage disease type 1b maps to chromosome 11q23.MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein functionThe leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusionsProteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localizationCpG binding protein is crucial for early embryonic developmentThe elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesisMLL and CREB bind cooperatively to the nuclear coactivator CREB-binding proteinSet domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteinsThe 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolutionEEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia
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P2860
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
description
1992 nî lūn-bûn
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1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@ast
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@en
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@nl
type
label
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@ast
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@en
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@nl
prefLabel
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@ast
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@en
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@nl
P2093
P3181
P1433
P1476
The t(4;11) chromosome translo ...... la trithorax, to the AF-4 gene
@en
P2093
T Nakamura
P3181
P356
10.1016/0092-8674(92)90603-A
P407
P577
1992-11-13T00:00:00Z