Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element
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A worldwide correlation of lactase persistence phenotype and genotypesGenetic signatures of strong recent positive selection at the lactase gene.Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk cultureConvergent adaptation of human lactase persistence in Africa and EuropeEvidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humansSystemic lactose intolerance: a new perspective on an old problemThe Diverse Forms of Lactose Intolerance and the Putative Linkage to Several CancersRecent human adaptation: genomic approaches, interpretation and insightsHow long have adult humans been consuming milk?Prevalence and trends in adult-type hypolactasia in different age cohorts in Central Sweden diagnosed by genotyping for the adult-type hypolactasia-linked LCT -13910C > T mutationComparison of lactase persistence polymorphism in ancient and present-day Hungarian populationsPredicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored AlleleGenetic variation and adaptation in Africa: implications for human evolution and diseaseEvolution of lactase persistence: an example of human niche constructionMolecular adaptation of modern human populationsAfrican genetic diversity: implications for human demographic history, modern human origins, and complex disease mappingAssociation of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysisCorrelation of G/A -22018 single-nucleotide polymorphism with lactase activity and its usefulness in improving the diagnosis of adult-type hypolactasia among North Indian children.Screening of variants for lactase persistence/non-persistence in populations from South Africa and Ghana.Evolutionary mutant models for human diseaseEuropean lactase persistence genotype shows evidence of association with increase in body mass indexGenome-wide scans for footprints of natural selection.Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.Genome-wide association studies: progress and potential for drug discovery and development.Lactase non-persistence and milk consumption in EstoniaMolecularly defined adult-type hypolactasia in school-aged children with a previous history of cow's milk allergy.Long-range control of gene expression: emerging mechanisms and disruption in disease.Temporal constraints on the incorporation of regulatory mutants in evolutionary pathwaysCorrelation of intestinal disaccharidase activities with the C/T-13910 variant and ageMolecularly defined adult-type hypolactasia among working age people with reference to milk consumption and gastrointestinal symptoms.13915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1Herders of Indian and European cattle share their predominant allele for lactase persistence.The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in AfricansMutations in the translated region of the lactase gene (LCT) underlie congenital lactase deficiencySeveral different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population.Distinguishing between selective sweeps from standing variation and from a de novo mutation.The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population.Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia.Molecular genetics of human lactase deficiencies.Theodore E. Woodward Award: lactase persistence SNPs in African populations regulate promoter activity in intestinal cell culture.
P2860
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P2860
Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Lactase persistence DNA varian ...... le as a cis regulatory element
@ast
Lactase persistence DNA varian ...... le as a cis regulatory element
@en
Lactase persistence DNA varian ...... le as a cis regulatory element
@nl
type
label
Lactase persistence DNA varian ...... le as a cis regulatory element
@ast
Lactase persistence DNA varian ...... le as a cis regulatory element
@en
Lactase persistence DNA varian ...... le as a cis regulatory element
@nl
prefLabel
Lactase persistence DNA varian ...... le as a cis regulatory element
@ast
Lactase persistence DNA varian ...... le as a cis regulatory element
@en
Lactase persistence DNA varian ...... le as a cis regulatory element
@nl
P3181
P356
P1476
Lactase persistence DNA varian ...... le as a cis regulatory element
@en
P2093
Eric Sibley
Lynne C Olds
P304
P3181
P356
10.1093/HMG/DDG244
P407
P577
2003-09-15T00:00:00Z