Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease
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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brainMeta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's diseaseLiver X receptors regulate cholesterol homeostasis in oligodendrocytesPlasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study.Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.Role of cholesterol 24S-hydroxylase gene polymorphism (rs754203) in primary open angle glaucoma.A pilot study of gene/gene and gene/environment interactions in Alzheimer disease.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculatureOverexpression of the IGF-II/M6P receptor in mouse fibroblast cell lines differentially alters expression profiles of genes involved in Alzheimer's disease-related pathologyNovel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neuronsAttenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors.Genetic association of CYP46 and risk for Alzheimer's disease.Cholesterol and apolipoprotein E in Alzheimer's disease.The link between cholesterol and Alzheimer's disease.The involvement of lipid rafts in Alzheimer's disease.Re-assessing the relationship between cholesterol, statins and Alzheimer's disease.Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitroABCA1-Mediated Cholesterol Efflux Capacity to Cerebrospinal Fluid Is Reduced in Patients With Mild Cognitive Impairment and Alzheimer's Disease.Oxysterols, cholesterol homeostasis, and Alzheimer disease.Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations.Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells.Regulation of tyrosine kinase B activity by the Cyp46/cholesterol loss pathway in mature hippocampal neurons: relevance for neuronal survival under stress and in aging.CYP46A1 T/C polymorphism associated with the APOE ε4 allele increases the risk of Alzheimer's disease.24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis.Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue.Polymorphism of CYP46A1 and PPARγ2 Genes in Risk Prediction of Primary Open Angle Glaucoma Among North Indian Population.Liver X Receptors as Therapeutic Targets for Managing Cholesterol: Implications for Atherosclerosis and Other Inflammatory ConditionsAssociation of CYP46 intron 2 polymorphism in Finnish Alzheimer's disease samples and a global scale summary.Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis.Polymorphism in the cholesterol 24S-hydroxylase gene (CYP46A1) associated with the APOEpsilon3 allele increases the risk of Alzheimer's disease and of mild cognitive impairment progressing to Alzheimer's disease.An intronic CYP46A1 polymorphism is associated with Alzheimer disease in a Chinese Han population.Frontiers of Complex Disease Mechanisms: Membrane Surface Tension May Link Genotype to Phenotype in Glaucoma.Interactions of amyloid β peptide 1-40 and cerebrosterol.Intron 2 (T/C) CYP46 polymorphism is associated with Alzheimer's disease in Chinese patients.
P2860
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P2860
Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease
description
2002 nî lūn-bûn
@nan
2002 թուականին հրատարակուած գիտական յօդուած
@hyw
2002 թվականին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@ast
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@en
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@nl
type
label
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@ast
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@en
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@nl
prefLabel
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@ast
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@en
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@nl
P2093
P2860
P3181
P356
P1433
P1476
Polymorphism in the cholestero ...... iated with Alzheimer's disease
@en
P2093
D Lütjohann
Heike Kölsch
K von Bergmann
P2860
P2888
P304
P3181
P356
10.1038/SJ.MP.4001109
P407
P50
P577
2002-01-01T00:00:00Z