The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya
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Complete genome sequence of Streptomyces cattleya NRRL 8057, a producer of antibiotics and fluorometabolitesDefinition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesisCarbapenems: past, present, and futureFour enzymes define the incorporation of coenzyme A in thienamycin biosynthesisRadical SAM-mediated methylation reactionsRadical-mediated enzymatic methylation: a tale of two SAMSConvergent biosynthetic pathways to β-lactam antibioticsStructure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum diseaseNon-heme iron oxygenases generate natural structural diversity in carbapenem antibioticsThe enzymes of β-lactam biosynthesis.Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin.Regulation and biosynthesis of carbapenem antibiotics in bacteria.Antibiotics from microbes: converging to kill.Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.Radical S-adenosylmethionine enzymes: mechanism, control and function.Origins of the β-lactam rings in natural products.Penicillin-binding proteins in Actinobacteria.Cyclization of polyketides and non-ribosomal peptides on and off their assembly lines.A conserved lysine in beta-lactam synthetase assists ring cyclization: Implications for clavam and carbapenem biosynthesis.A Combinatorial Algorithm for Microbial Consortia Synthetic DesignDiscovery of 3-formyl-tyrosine metabolites from Pseudoalteromonas tunicata through heterologous expression.Complete characterization of the seventeen step moenomycin biosynthetic pathway.Mutational analysis of the thienamycin biosynthetic gene cluster from Streptomyces cattleya.Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.Stereoselective preparation of lipidated carboxymethyl-proline/pipecolic acid derivatives via coupling of engineered crotonases with an alkylmalonyl-CoA synthetase.Activation and silencing of secondary metabolites in Streptomyces albus and Streptomyces lividans after transformation with cosmids containing the thienamycin gene cluster from Streptomyces cattleya.Enhanced Solubilization of Class B Radical S-adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli.TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase.Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis
P2860
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P2860
The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@ast
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@en
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@nl
type
label
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@ast
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@en
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@nl
prefLabel
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@ast
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@en
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@nl
P50
P3181
P1476
The biosynthetic gene cluster ...... mycin in Streptomyces cattleya
@en
P2093
José A Salas
Luz Elena Núñez
P304
P3181
P356
10.1016/S1074-5521(03)00069-3
P407
P577
2003-04-01T00:00:00Z