Episodic ataxia type-1 mutations in the Kv1.1 potassium channel display distinct folding and intracellular trafficking properties
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Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndromeA truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction.New insights into the pathogenesis and therapeutics of episodic ataxia type 1Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segmentADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axonsClustered K+ channel complexes in axonsVoltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration.Developmental expression of Kv potassium channels at the axon initial segment of cultured hippocampal neuronsDeterminants of voltage-gated potassium channel surface expression and localization in Mammalian neurons.Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel.Subunit-dependent axonal trafficking of distinct alpha heteromeric potassium channel complexesA novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.Ubiquitylation of ion channels.Role of the hydrophobic domain in targeting caveolin-1 to lipid droplets.The episodic ataxia type 1 mutation I262T alters voltage-dependent gating and disrupts protein biosynthesis of human Kv1.1 potassium channels.Surface expression and distribution of voltage-gated potassium channels in neurons (Review).Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking.Regulation of Kv1 channel trafficking by the mamba snake neurotoxin dendrotoxin K.Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.Episodic ataxia type 1 mutations differentially affect neuronal excitability and transmitter release.Identification of an evolutionarily conserved extracellular threonine residue critical for surface expression and its potential coupling of adjacent voltage-sensing and gating domains in voltage-gated potassium channels.The degree of N-glycosylation affects the trafficking and cell surface expression levels of Kv1.4 potassium channels.A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists.Oligodendrogenesis is differentially regulated in gray and white matter of jimpy mice.Amino Acid Properties of Trafficking Determinants in the Outer Pore-Forming Region of Kv1 Potassium Channels in Cell Lines.Kv1 potassium channel C-terminus constant HRETE region: arginine substitution affects surface protein level and conductance level of subfamily members differentially.
P2860
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P2860
Episodic ataxia type-1 mutations in the Kv1.1 potassium channel display distinct folding and intracellular trafficking properties
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@ast
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@en
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@nl
type
label
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@ast
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@en
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@nl
prefLabel
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@ast
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@en
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@nl
P2093
P356
P1476
Episodic ataxia type-1 mutatio ...... ellular trafficking properties
@en
P2093
C R Campomanes
D E Antonucci
J S Trimmer
L N Manganas
P304
P356
10.1074/JBC.M109325200
P407
P577
2001-12-28T00:00:00Z