The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor - Wikidata - awgldk - TriplyDB

The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor

The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor

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Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2 Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1 Crystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1 Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activation Matriptase autoactivation is tightly regulated by the cellular chemical environments Evidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytes Roles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptase Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta Protein interaction analysis of ST14 domains and their point and deletion mutants.Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis.Local protease signaling contributes to neural tube closure in the mouse embryo Matriptase activation, an early cellular response to acidosis.Matriptase zymogen supports epithelial development, homeostasis and regeneration TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells N-glycosylation is required for matriptase-2 autoactivation and ectodomain shedding Membrane-anchored serine proteases in vertebrate cell and developmental biology Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin.Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation Matriptase is involved in ErbB-2-induced prostate cancer cell invasion Distinct roles of N-glycosylation at different sites of corin in cell membrane targeting and ectodomain shedding.A pan-cancer analysis of alternative splicing events reveals novel tumor-associated splice variants of matriptase.Role of glycosylation in corin zymogen activation.Increased matriptase zymogen activation in inflammatory skin disorders.Antithrombin regulates matriptase activity involved in plasmin generation, syndecan shedding, and HGF activation in keratinocytes.Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity Matriptase: potent proteolysis on the cell surface.Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1 Detection of active matriptase using a biotinylated chloromethyl ketone peptide HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase.Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells Expression of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 in normal and malignant tissues of gastrointestinal tract.Prostasin: An Epithelial Sodium Channel Regulator.Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase.

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P2860

The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor

http://www.wikidata.org/entity/Q28203364

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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The activation of matriptase r ...... ain, and its cognate inhibitor

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P1433

Journal of Biological Chemistry

P1476

The activation of matriptase r ...... ain, and its cognate inhibitor

@en

P2093

Chen-Yong Lin

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Cicely A Williams

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Michael D Johnson

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Michael D Oberst

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Robert B Dickson

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P2860

Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo

Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module

Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk

Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention

Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

Prometastatic effect of N-acetylglucosaminyltransferase V is due to modification and stabilization of active matriptase by adding beta 1-6 GlcNAc branching

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26773-9

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scholarly article

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2579849

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10.1074/JBC.M304282200

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P433

29

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P478

278

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P577

2003-07-18T00:00:00Z

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P698

12738778

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