Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation
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Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeletonMutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4HCharcot-Marie-Tooth disease and intracellular trafficPhosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitorsInvolvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells.Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells.Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge.Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membraneThe effects of cytotoxic necrotizing factor 1 expression in the uptake of Escherichia coli K1 by macrophages and the onset of meningitis in newborn mice.Charcot-Marie-Tooth Disease Type 4H Resulting from Compound Heterozygous Mutations in FGD4 from Nonconsanguineous Korean Families.Association of frabin with specific actin and membrane structures.The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.
P2860
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P2860
Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@ast
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@en
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@nl
type
label
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@ast
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@en
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@nl
prefLabel
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@ast
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@en
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@nl
P2093
P2860
P921
P356
P1433
P1476
Cooperation of Cdc42 small G p ...... frabin in microspike formation
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204463
P407
P577
2001-06-01T00:00:00Z
P5875
P6179
1050941976