Kinetic and mechanical basis of rolling through an integrin and novel Ca2+-dependent rolling and Mg2+-dependent firm adhesion modalities for the alpha 4 beta 7-MAdCAM-1 interaction
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Remodeling of the lectin-EGF-like domain interface in P- and L-selectin increases adhesiveness and shear resistance under hydrodynamic forceMelatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kappaBControl of CD8 T-Cell Infiltration into Tumors by Vasculature and MicroenvironmentTransmission of allostery through the lectin domain in selectin-mediated cell adhesion.L-selectin-mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding eventsKinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates.Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stressThe CC' and DE loops in Ig domains 1 and 2 of MAdCAM-1 play different roles in MAdCAM-1 binding to low- and high-affinity integrin alpha4beta7Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.Importance of force linkage in mechanochemistry of adhesion receptors.Identification, characterization, and epitope mapping of human monoclonal antibody J19 that specifically recognizes activated integrin α4β7.Simultaneous tether extraction from endothelial cells and leukocytes: observation, mechanics, and significance.Avidity enhancement of L-selectin bonds by flow: shear-promoted rotation of leukocytes turn labile bonds into functional tethers.Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletionsThe unique disulfide bond-stabilized W1 β4-β1 loop in the α4 β-propeller domain regulates integrin α4β7 affinity and signaling.Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow ConditionsTwo-dimensional kinetics of beta 2-integrin and ICAM-1 bindings between neutrophils and melanoma cells in a shear flow.
P2860
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P2860
Kinetic and mechanical basis of rolling through an integrin and novel Ca2+-dependent rolling and Mg2+-dependent firm adhesion modalities for the alpha 4 beta 7-MAdCAM-1 interaction
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@ast
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@en
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@nl
type
label
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@ast
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@en
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@nl
prefLabel
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@ast
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@en
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@nl
P2093
P1433
P1476
Kinetic and mechanical basis o ...... 4 beta 7-MAdCAM-1 interaction
@en
P2093
P304
P407
P577
2001-11-20T00:00:00Z