Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4
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HSV-1 ICP27 suppresses NF-kappaB activity by stabilizing IkappaBalphaPIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive elementRegulation of gene-activation pathways by PIAS proteins in the immune systemAssociation of Ubc9, an E2 ligase for SUMO conjugation, with p53 is regulated by phosphorylation of p53PIAS1 activates the expression of smooth muscle cell differentiation marker genes by interacting with serum response factor and class I basic helix-loop-helix proteins.Protein inhibitor of activated STAT, PIASy regulates α-smooth muscle actin expression by interacting with E12 in mesangial cellsPIAS1 mediates TGFbeta-induced SM alpha-actin gene expression through inhibition of KLF4 function-expression by protein sumoylationMultiple activities contribute to Pc2 E3 function.Protein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5.TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPKCrosstalk between the p38 and TGF-β signaling pathways through TβRI, TβRII and Smad3 expression in plancental choriocarcinoma JEG-3 cells.Emerging roles of SUMO modification in arthritis.Functional reconstitution of a tunable E3-dependent sumoylation pathway in Escherichia coli.Lamin A/C mutants disturb sumo1 localization and sumoylation in vitro and in vivo.Transcriptional activity of megakaryoblastic leukemia 1 (MKL1) is repressed by SUMO modification.The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.Small ubiquitin-like modifier modification regulates the DNA binding activity of glial cell missing Drosophila homolog a.dickkopf-3-related gene regulates the expression of zebrafish myf5 gene through phosphorylated p38a-dependent Smad4 activity.SUMO Proteins are not Involved in TGF-β1-induced, Smad3/4-mediated Germline α Transcription, but PIASy Suppresses it in CH12F3-2A B CellsTransforming growth factor-β and the hallmarks of cancer.Regulation of transforming growth factor-β1-dependent integrin β6 expression by p38 mitogen-activated protein kinase in bile duct epithelial cellsTransforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene.Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors.Regulation of Smad activities.TGF-beta signaling in chondrocytes.Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cellsCurcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice.Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SADTo (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modificationsRegulating the stability of TGFbeta receptors and Smads.TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling.Role of Smads in TGFβ signaling.Post-translational regulation of TGF-β receptor and Smad signaling.SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.Transcriptional repression by sumoylation of Epstein-Barr virus BZLF1 protein correlates with association of histone deacetylase.Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E.The ubiquitin-like protein MNSFbeta regulates ERK-MAPK cascade.Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4.
P2860
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P2860
Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4
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2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@ast
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@en
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@nl
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label
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@ast
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@en
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@nl
prefLabel
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@ast
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@en
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@nl
P2860
P356
P1476
Transforming growth factor-bet ...... h SUMO-1 modification of Smad4
@en
P2093
Kunitada Shimotohno
Takayuki Ohshima
P2860
P304
P356
10.1074/JBC.M307533200
P407
P577
2003-12-19T00:00:00Z