Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation
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Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1Ubiquitin-Mediated Degradation of Aurora KinasesDual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit.Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insightsThe Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiaePseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation.Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicitySUMOylation inhibits FOXM1 activity and delays mitotic transition.Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons.The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress.APC/C-CCS52A complexes control meristem maintenance in the Arabidopsis rootNuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylationThe anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sitesTargeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma.Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.GPS-ARM: computational analysis of the APC/C recognition motif by predicting D-boxes and KEN-boxes.Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation.Modulation of the unfolded protein response by the severe acute respiratory syndrome coronavirus spike protein.Phosphorylation of ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) by Akt promotes stability and mitogenic function of S-phase kinase-associated protein-2 (Skp2).Endoreduplication and activation of the anaphase-promoting complex during symbiotic cell development.Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells.Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle.TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal SurvivalThe emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression.Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.Fulfilling the metabolic requirements for cell proliferation.REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis.NEK7 is required for G1 progression and procentriole formation.Two classes of the CDh1-type activators of the anaphase-promoting complex in plants: novel functional domains and distinct regulation.Nuclear survivin has reduced stability and is not cytoprotective.Endoreduplication mediated by the anaphase-promoting complex activator CCS52A is required for symbiotic cell differentiation in Medicago truncatula nodules.T-cadherin is located in the nucleus and centrosomes in endothelial cells.
P2860
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P2860
Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Nuclear localization of the ce ...... regulation by phosphorylation
@ast
Nuclear localization of the ce ...... regulation by phosphorylation
@en
Nuclear localization of the ce ...... regulation by phosphorylation
@nl
type
label
Nuclear localization of the ce ...... regulation by phosphorylation
@ast
Nuclear localization of the ce ...... regulation by phosphorylation
@en
Nuclear localization of the ce ...... regulation by phosphorylation
@nl
prefLabel
Nuclear localization of the ce ...... regulation by phosphorylation
@ast
Nuclear localization of the ce ...... regulation by phosphorylation
@en
Nuclear localization of the ce ...... regulation by phosphorylation
@nl
P2093
P2860
P3181
P356
P1476
Nuclear localization of the ce ...... regulation by phosphorylation
@en
P2093
Abel C S Chun
Dong-Yan Jin
Yick-Pang Ching
P2860
P304
P3181
P356
10.1074/JBC.M212853200
P407
P577
2003-04-04T00:00:00Z