Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities
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A protein interaction framework for human mRNA degradationMPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturationUNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinantC1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processingeIF4G is required for the pioneer round of translation in mammalian cellsNematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpSDegradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'Addition of poly(A) and poly(A)-rich tails during RNA degradation in the cytoplasm of human cellsNuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage.Multiple mRNA decapping enzymes in mammalian cellsHuman cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathwaysSMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoanRegulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translationEvolutionary conservation supports ancient origin for Nudt16, a nuclear-localized, RNA-binding, RNA-decapping enzymeHuman 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sitesThe human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3LDis3-like 1: a novel exoribonuclease associated with the human exosomeUpf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decayZinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradationThe zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNAMultiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins.RNA splicing capability of live neuronal dendritesTethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayCompetency for nonsense-mediated reduction in collagen X mRNA is specified by the 3' UTR and corresponds to the position of mutations in Schmid metaphyseal chondrodysplasiaCytoplasmic foci are sites of mRNA decay in human cellsAlternative splicing and protein functionNonsense-mediated mRNA decay: novel mechanistic insights and biological impactThe 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human DiseaseThe dharma of nonsense-mediated mRNA decay in mammalian cellsNonsense-mediated mRNA decay: inter-individual variability and human diseaseThe crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosomeRegulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex.Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.Assembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47Targeting of aberrant mRNAs to cytoplasmic processing bodies.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryRecruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1Messenger RNA turnover in eukaryotes: pathways and enzymesLocalization of AU-rich element-containing mRNA in cytoplasmic granules containing exosome subunits
P2860
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P2860
Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@ast
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@en
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@nl
type
label
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@ast
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@en
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@nl
prefLabel
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@ast
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@en
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@nl
P3181
P1433
P1476
Nonsense-mediated mRNA decay i ...... and exonucleolytic activities
@en
P2093
Xiaojie Li
P304
P3181
P356
10.1016/S1097-2765(03)00349-6
P407
P577
2003-09-01T00:00:00Z