Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family
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Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionIdentification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosisThe human SWI/SNF subunit Brm is a regulator of alternative splicingBimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosisJNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosisRegulation of Bim in Health and DiseaseBim nuclear translocation and inactivation by viral interferon regulatory factor.BH3-only proteins in apoptosis and beyond: an overview.Bcl-rambo beta, a special splicing variant with an insertion of an Alu-like cassette, promotes etoposide- and Taxol-induced cell death.Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons.Anti-apoptotic activity and proteasome-mediated degradation of Xenopus Mcl-1 protein in egg extracts.A single nucleotide polymorphism in cBIM is associated with a slower achievement of major molecular response in chronic myeloid leukaemia treated with imatinibThe splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation.Follicle-stimulating hormone regulates pro-apoptotic protein Bcl-2-interacting mediator of cell death-extra long (BimEL)-induced porcine granulosa cell apoptosisThe major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer.Cellular responses to HSV-1 infection are linked to specific types of alterations in the host transcriptome.Therapeutic modulation of apoptosis: targeting the BCL-2 family at the interface of the mitochondrial membrane.The role of the ubiquitin proteasome system in ischemia and ischemic tolerance.Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway.Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition.Zinc-induced modulation of SRSF6 activity alters Bim splicing to promote generation of the most potent apoptotic isoform BimS.Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL.Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes.Bim inhibits autophagy by recruiting Beclin 1 to microtubules.Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia.TGFbeta-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL.
P2860
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P2860
Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@ast
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@en
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@nl
type
label
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@ast
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@en
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@nl
prefLabel
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@ast
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@en
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@nl
P2093
P2860
P3181
P1433
P1476
Molecular cloning and characte ...... the proapoptotic Bcl-2 family
@en
P2093
P2860
P304
P3181
P356
10.1016/S0014-5793(01)03145-3
P407
P577
2001-11-30T00:00:00Z