Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
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ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected]Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinaseMutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethalQuaternary structure of human fatty acid synthase by electron cryomicroscopy.Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscleGene knockout of Acc2 has little effect on body weight, fat mass, or food intakeThe ancient drug salicylate directly activates AMP-activated protein kinaseThe human ACC2 CT-domain C-terminus is required for full functionality and has a novel twistChronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolismCrystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanismAcetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate dietsEffect of food deprivation and hormones of glucose homeostasis on the acetyl CoA carboxylase activity in mouse brain: a potential role of acc in the regulation of energy balance.Nutrigenomics and Beef Quality: A Review about LipogenesisFatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancerMetabolism Is Central to Tolerogenic Dendritic Cell Function'Micro-managers' of hepatic lipid metabolism and NAFLDGenome-wide association studies of chronic kidney disease: what have we learned?Structure and function of biotin-dependent carboxylasesNovel roles of holocarboxylase synthetase in gene regulation and intermediary metabolismAMPK: a cellular metabolic and redox sensor. A minireviewThe potential of ¹¹C-acetate PET for monitoring the Fatty acid synthesis pathway in TumorsEnergy metabolism in the liverFueling immunity: insights into metabolism and lymphocyte functionThe dynamic organization of fungal acetyl-CoA carboxylase.Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient miceTemporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and BioenergeticsA different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydimMechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxadenStructure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site ConversionObesity and cancer progression: is there a role of fatty acid metabolism?C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolismC75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinaseAdipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammationHuman Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell DeathDrosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory systemGlucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout miceSterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubesIsozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animalsReduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice
P2860
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P2860
Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@ast
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@en
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@nl
type
label
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@ast
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@en
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@nl
prefLabel
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@ast
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@en
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@nl
P2093
P3181
P356
P1433
P1476
Continuous fatty acid oxidatio ...... cking acetyl-CoA carboxylase 2
@en
P2093
K A Abo-Hashema
L Abu-Elheiga
M M Matzuk
P304
P3181
P356
10.1126/SCIENCE.1056843
P407
P577
2001-03-30T00:00:00Z