A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
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Human cytomegalovirus resistance to antiviral drugsUpdate on human herpesvirus 6 biology, clinical features, and therapyNeuropathogenesis of congenital cytomegalovirus infection: disease mechanisms and prospects for interventionDetermination and analysis of the complete nucleotide sequence of human herpesvirusCytomegalovirus antivirals and development of improved animal modelsGanciclovir ophthalmic gel 0.15% for the treatment of acute herpetic keratitis: background, effectiveness, tolerability, safety, and future applicationsApproved Antiviral Drugs over the Past 50 YearsAntiviral drug resistance in human cytomegalovirusPhosphorylation of beta-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirusInhibition of human cytomegalovirus in culture by alkenyl guanine analogs of the thiazolo[4,5-d]pyrimidine ring systemIn vitro antiviral activity of penciclovir, a novel purine nucleoside, against duck hepatitis B virusHuman cytomegalovirus: challenges, opportunities and new drug developmentAntiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early regionAnalysis of phosphorylation pathways of antiherpesvirus nucleosides by varicella-zoster virus-specific enzymesInhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene productResistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56Antiviral drug resistance of human cytomegalovirus.Viral and cell cycle-regulated kinases in cytomegalovirus-induced pseudomitosis and replication.Resistance of human cytomegalovirus to antiviral drugs.Cellular elongation factor 1delta is modified in cells infected with representative alpha-, beta-, or gammaherpesvirusesA protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro.New strategies for prevention and therapy of cytomegalovirus infection and disease in solid-organ transplant recipientsClinical uses of cidofovir.Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.A standardized plaque reduction assay for determination of drug susceptibilities of cytomegalovirus clinical isolates.Emergence of multiple human cytomegalovirus ganciclovir-resistant mutants with deletions and substitutions within the UL97 gene in a patient with severe combined immunodeficiency.Induction of Epstein-Barr virus kinases to sensitize tumor cells to nucleoside analoguesDistinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation.Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitroMutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma.Use of adenovirus vectors expressing Epstein-Barr virus (EBV) immediate-early protein BZLF1 or BRLF1 to treat EBV-positive tumors.Relationship between autophosphorylation and phosphorylation of exogenous substrates by the human cytomegalovirus UL97 protein kinase.Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8.Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections.Cytomegalovirus drug resistance and clinical implications.Human cytomegalovirus UL97 kinase and nonkinase functions mediate viral cytoplasmic secondary envelopment.Infection of human cytomegalovirus in cultured human gingival tissue.Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovirDetection of human cytomegalovirus mutations associated with ganciclovir resistance in cerebrospinal fluid of AIDS patients with central nervous system disease.The guanine nucleoside analog penciclovir is active against chronic duck hepatitis B virus infection in vivo.
P2860
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P2860
A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
A protein kinase homologue con ...... cytomegalovirus-infected cells
@ast
A protein kinase homologue con ...... cytomegalovirus-infected cells
@en
A protein kinase homologue con ...... cytomegalovirus-infected cells
@nl
type
label
A protein kinase homologue con ...... cytomegalovirus-infected cells
@ast
A protein kinase homologue con ...... cytomegalovirus-infected cells
@en
A protein kinase homologue con ...... cytomegalovirus-infected cells
@nl
prefLabel
A protein kinase homologue con ...... cytomegalovirus-infected cells
@ast
A protein kinase homologue con ...... cytomegalovirus-infected cells
@en
A protein kinase homologue con ...... cytomegalovirus-infected cells
@nl
P2093
P356
P1433
P1476
A protein kinase homologue con ...... cytomegalovirus-infected cells
@en
P2093
P2507
P2888
P356
10.1038/358162A0
P407
P577
1992-07-09T00:00:00Z
P6179
1004244055