Functional expression of the canalicular bile salt export pump of human liver
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Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variabilityBile acid transporters in health and diseaseBile acid transportersEvidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in manFarnesoid X receptor regulates bile acid-amino acid conjugationMissense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicingFXR regulates liver repair after CCl4-induced toxic injuryDetergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastorisTemporal expression profiles of organic anion transport proteins in placenta and fetal liver of the ratThe role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type IIVectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pumpClinical application of transcriptional activators of bile salt transporters.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Bile formation and secretion.Heterologous overexpression and mutagenesis of the human bile salt export pump (ABCB11) using DREAM (Directed REcombination-Assisted Mutagenesis).Intractable itch relieved by 4-phenylbutyrate therapy in patients with progressive familial intrahepatic cholestasis type 1Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over farsenoid X receptor-mediated antagonismGenome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver diseaseMouse Bsep ATPase assay: a nonradioactive tool for assessment of the cholestatic potential of drugs.The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEPGenetics of familial intrahepatic cholestasis syndromes.Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.Diagnosis in bile acid-CoA: amino acid N-acyltransferase deficiency.Analysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches.Hepatobiliary transport in health and diseaseLiver receptor homolog 1 transcriptionally regulates human bile salt export pump expression.Prediction of drug-induced intrahepatic cholestasis: in vitro screening and QSAR analysis of drugs inhibiting the human bile salt export pump.Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pumpBiosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Bile Acid sulfation: a pathway of bile acid elimination and detoxification.Technical pitfalls and improvements for high-speed screening and QSAR analysis to predict inhibitors of the human bile salt export pump (ABCB11/BSEP).A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy.Role of the bile salt export pump, BSEP, in acquired forms of cholestasis.Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4.Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis.Canalicular ABC transporters and liver disease.
P2860
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P2860
Functional expression of the canalicular bile salt export pump of human liver
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Functional expression of the canalicular bile salt export pump of human liver
@ast
Functional expression of the canalicular bile salt export pump of human liver
@en
Functional expression of the canalicular bile salt export pump of human liver
@nl
type
label
Functional expression of the canalicular bile salt export pump of human liver
@ast
Functional expression of the canalicular bile salt export pump of human liver
@en
Functional expression of the canalicular bile salt export pump of human liver
@nl
prefLabel
Functional expression of the canalicular bile salt export pump of human liver
@ast
Functional expression of the canalicular bile salt export pump of human liver
@en
Functional expression of the canalicular bile salt export pump of human liver
@nl
P2093
P3181
P356
P1433
P1476
Functional expression of the canalicular bile salt export pump of human liver
@en
P2093
Bruno Stieger
Johannes Noé
Peter J Meier
P304
P3181
P356
10.1053/GAST.2002.36587
P407
P577
2002-11-01T00:00:00Z