Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways
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Inhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemiaUse of whole-genome sequencing to diagnose a cryptic fusion oncogene.Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cellsStat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end.Curing all patients with acute promyelocytic leukemia: are we there yet?To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.Cross-talk between retinoic acid and STAT3 signaling pathways in acute promyelocytic leukemia.Development of real-time quantitative polymerase chain reaction assays to track treatment response in retinoid resistant acute promyelocytic leukemia.Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell levelStat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphomaFrom molecular interaction to acute promyelocytic leukemia: Calculating leukemogenesis and remission from endogenous molecular-cellular network.Myeloid neoplasm demonstrating a STAT5B-RARA rearrangement and genetic alterations associated with all-trans retinoic acid resistance identified by a custom next-generation sequencing assay.Stat5 as a diagnostic marker for leukemia.Regulation of FoxP3 regulatory T cells and Th17 cells by retinoids.RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma.Targeting signal transducer and activator of transcription signaling pathway in leukemias.Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha.All-trans retinoic acid in the treatment of pediatric acute promyelocytic leukemia.STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells.RARA fusion genes in acute promyelocytic leukemia: a review.Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5.Molecular Mechanisms of the Action of Vitamin A in Th17/Treg Axis in Multiple Sclerosis.Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 bindingCritical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia.The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation.Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2.Microgranular and t(11;17)/PLZF-RARalpha variants of acute promyelocytic leukemia also present the flow cytometric pattern of CD13, CD34, and CD15 expression characteristic of PML-RARalpha gene rearrangement.JAK-STAT signaling regulation of chicken embryonic stem cell differentiation into male germ cells.Translocation t(11;17) in de novo myelodysplastic syndrome not associated with acute myeloid or acute promyelocytic leukemia.A new acute myeloid leukemia case with STAT5B-RARA gene fusion due to 17q21.2 interstitial deletion.
P2860
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P2860
Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways
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2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2002 թվականի ապրիլին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@ast
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@en
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@nl
type
label
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@ast
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@en
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@nl
prefLabel
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@ast
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@en
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@nl
P3181
P356
P1433
P1476
Interactions of STAT5b-RARalph ...... r and STAT3 signaling pathways
@en
P2093
David J Tweardy
P304
P3181
P356
10.1182/BLOOD.V99.8.2637
P407
P577
2002-04-15T00:00:00Z