Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas - Wikidata - awgldk - TriplyDB

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

http://www.wikidata.org/entity/Q28213290

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Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression The links between axin and carcinogenesis Regenerating the liver: not so simple after all?Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment Current and future treatments for hepatocellular carcinoma Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma Aberrant regulation of Wnt signaling in hepatocellular carcinoma β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network Expression of axin2 is regulated by the alternative 5'-untranslated regions of its mRNA Tumor suppressor and hepatocellular carcinoma Dickkopfs and Wnt/β-catenin signalling in liver cancer Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin DNA methylation: potential biomarker in Hepatocellular Carcinoma.Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma.DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.Identification of drivers from cancer genome diversity in hepatocellular carcinoma.Role of Wnt/β-catenin signaling in liver metabolism and cancer Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis.Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer.Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of beta-catenin in the liver.Experimental models of hepatocellular carcinoma Molecular profiling of hepatocellular carcinomas by cDNA microarray.Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.β-catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase M3 mRNA.Axin gene methylation status correlates with radiosensitivity of lung cancer cells Novel therapeutic strategies for targeting liver cancer stem cells.Effect of mutant β-catenin on liver growth homeostasis and hepatocarcinogenesis in transgenic mice Clinical significance of aberrant Wnt7a promoter methylation in human non-small cell lung cancer in Koreans

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Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

http://www.wikidata.org/entity/Q28213290

description

2002 nî lūn-bûn

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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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type

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Mutational spectrum of beta-ca ...... carcinomas and hepatoblastomas

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Chiping Qian

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David I Smith

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David M Nagorney

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Ileana N Aderca

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Julie A Ross

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Ken Taniguchi

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Lawrence J Burgart

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Lewis R Roberts

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Linda M Murphy

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Patrick C Roche

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P2860

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis

Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23-q24

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

Genomic structure, chromosome mapping and expression analysis of the human AXIN2 gene

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

Functional interaction of beta-catenin with the transcription factor LEF-1

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

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10.1038/SJ.ONC.1205591

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21

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1046509421

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