Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions - Wikidata - awgldk - TriplyDB

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

http://www.wikidata.org/entity/Q28214350

about

sameAs

Involvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesion CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.Structural basis for amplifying vinculin activation by talin The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha Phospholipase D activity is essential for actin localization and actin-based motility in Dictyostelium Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexes ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signaling The integrin-actin connection, an eternal love affair Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation Mechanosensitive components of integrin adhesions: Role of vinculin Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets Phosphoinositides: tiny lipids with giant impact on cell regulation Lipid kinases as therapeutic targets for chronic pain Regulation of platelet plug formation by phosphoinositide metabolism Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment.TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility PIPKIγ regulates focal adhesion dynamics and colon cancer cell invasion The Structure of an Interdomain Complex That Regulates Talin Activity Molecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2 Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes PIP kinases define PI4,5P₂signaling specificity by association with effectors Emerging roles of PtdIns(4,5)P2--beyond the plasma membrane Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling Identification and characterization of a phosphoinositide phosphate kinase homolog A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma Mechanism of Focal Adhesion Kinase Mechanosensing A novel testis ubiquitin-binding protein gene arose by exon shuffling in hominoids

P2860

Q24298800-BE4E76CA-0D4D-41F4-A695-1335673D6811 Q24318270-BC55625E-5AFD-41D0-81C7-696009B61079 Q24319973-65684344-BD7C-4A25-B469-15689F61A3E5 Q24336004-261049CB-C809-4BD2-ABA7-8D58D51703D3 Q24523657-6BC64CF7-F4A9-4F1E-8284-F325DBB86D9D Q24534889-FB7A5351-9C51-4678-9ED2-2E5907C3B8F5 Q24563216-50961E33-7D1E-4BAE-9984-FE0FAB07C484 Q24602665-690BB959-CCC3-415B-B7A5-9CAE2B005875 Q24671026-C2E941A7-1321-4670-836D-47B155E9AD2A Q24675779-F8B3F76F-A68D-4D57-BCF1-40F0CD0094B7 Q24676005-13238C93-4192-4705-9B8A-2BAE14EC483B Q24676735-2D6264A6-954E-427A-AE48-9209468C1B86 Q24683598-22F5249F-8B95-4628-8B4C-7D4B7576DEE5 Q26744638-533D595B-9A1D-49F8-A5D0-52D4A1E2ADA6 Q26775432-8C195F14-4E58-434E-A972-74EAD9E28121 Q26998976-D7970D29-2DDF-4BD7-BFBF-287D1A169F58 Q27012953-CC5D60FF-7D00-4484-A124-FAB639AB1207 Q27023075-A4C759A0-EFE7-4314-99E5-76FA90FB182E Q27025414-C0743459-D3B0-4EF5-918B-02DD3DF0B484 Q27302315-27F3BCF9-D0E2-4A2A-AF5F-9509CE0C70E0 Q27303922-C36B39DA-AA8B-4BE0-8B4E-03C188553A78 Q27320345-23390F87-0138-4F35-BA5A-60BD850C8460 Q27654202-E56815BF-B1C7-4517-BE01-80FCEFE09887 Q27658124-F63C2362-87A4-4643-B8C8-DFCC699F2B30 Q27659768-5818AABF-5DD6-42DF-B038-25DAC80FB32B Q27665036-27198BED-11E5-4DB1-889B-CFBED749D177 Q27675529-5CBE8ED4-5109-4F46-A36F-628F8BC938DC Q27681229-C03466C7-043E-49EA-AA12-8B39DD9F5EFF Q27684765-45FCC320-844E-4FED-A30B-EF8B765FD4A9 Q28083975-05C73903-53AD-4D5B-ABD3-F8382DDDBE55 Q28084524-8EA41908-E1F9-4FDD-8016-2712A17AD4D1 Q28189437-067D9698-DD3C-4292-B155-75127EA914B3 Q28236826-19851CD1-D7DA-45DE-B2F1-8DF380C67AE1 Q28477989-0CDB11C8-09CC-4E8E-B6DB-76D4A822AA41 Q28506114-62D18187-62B4-4C75-A83E-C91FCBA438AE Q28506799-FAC82CE6-7DB1-4AF8-BA0C-27DD6F2EB4D8 Q28508195-43D8E438-03BE-45DA-ABB7-418AAEF7EE09 Q28508645-8ADAC9B5-6B42-4662-9053-E691EA9FDE26 Q28550745-873A04FD-DBEF-4B39-ACAA-E4BFB8834CD2 Q28757273-33F72ADE-16EE-4594-B873-C2C9CEA33D36

P2860

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

http://www.wikidata.org/entity/Q28214350

description

2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Nature

@fr

artículu científicu espublizáu en 2002

@ast

scientific article (publication date: 7 November 2002)

@en

vedecký článok (publikovaný 2002/11/07)

@sk

vědecký článek publikovaný v roce 2002

@cs

wetenschappelijk artikel (gepubliceerd op 2002/11/07)

@nl

наукова стаття, опублікована в листопаді 2002

@uk

مقالة علمية (نشرت في 7-11-2002)

@ar

name

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@ast

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@en

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@nl

type

label

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@ast

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@en

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@nl

prefLabel

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@ast

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@en

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@nl

P1433

Q28214350-AFCA7563-6ED8-4679-8095-A551A59662F5

P1476

Q28214350-EB80294D-B825-411C-BB39-7F45A75A5B87

P2093

Q28214350-81A7309C-1EE1-4FCF-A819-FA9BDD8D6A63

Q28214350-CF527686-61E0-460C-B214-7E353EBF4EC3

Q28214350-DFC02273-8363-4829-8091-DB76904670AC

P2860

Q28214350-08A94F8D-7BC5-4658-97B4-5FF720030FA5

Q28214350-08FD59EF-CCB8-4325-AF79-0C6233B5BED2

Q28214350-0E5AD3D9-061F-49D4-90FC-9B0E3BD45578

Q28214350-0EC519E0-4F75-42F9-8779-1EFBA65299F4

Q28214350-BAD4C1EB-BB85-40B5-8B6B-5B0315D2B354

Q28214350-E283E529-3FD5-4A5F-82CE-10ACEA29576E

Q28214350-EC13E77D-95F3-4A17-9027-3A2A4937CCF4

P2888

Q28214350-A9002A46-7F99-4E35-A7CB-B8D463757E3F

P304

Q28214350-318FC349-EED9-401B-B50D-A2AADFBB5613

P31

Q28214350-E8239023-7F5C-4473-8FFE-7A9801C71B92

P3181

Q28214350-5253205E-6093-4CE0-88BE-14C88046934E

P356

Q28214350-CD9A8484-86BA-48F6-B457-ACF1885B9B0B

P407

Q28214350-9E753F73-7807-4C0E-A5CA-03666D5C2103

P433

Q28214350-754AD1AA-657A-4E19-A731-CFB269156A01

P478

Q28214350-1E7554C3-ED23-40EA-AEB5-7C78A53A55F7

P50

Q28214350-237A0617-451A-4C25-B550-26AE4A223560

Q28214350-7D1C4AD2-CBBD-44DB-9AAD-D7D9B035639F

P577

Q28214350-09E58CA8-CBA4-4390-9D68-E8CF916DBBF7

P6179

Q28214350-AD30459E-F239-49B9-A236-295CDA473ED1

P698

Q28214350-1E1BDE5F-BBF9-4ADF-BA6A-0D09B5067AAD

P3181

P356

P1433

P1476

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

@en

P2093

Kun Ling

http://www.w3.org/2001/XMLSchema#string

Matthew W Bunce

http://www.w3.org/2001/XMLSchema#string

Renee L Doughman

http://www.w3.org/2001/XMLSchema#string

P2860

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family

The phosphotyrosine binding-like domain of talin activates integrins

Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

Focal adhesions, contractility, and signaling

Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules

P2888

P304

89-93

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1644129

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NATURE01082

http://www.w3.org/2001/XMLSchema#string

P407

P433

6911

http://www.w3.org/2001/XMLSchema#string

P478

420

http://www.w3.org/2001/XMLSchema#string

P50

Ari J Firestone

Richard A. Anderson

P577

2002-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1037340946

http://www.w3.org/2001/XMLSchema#string

P698

12422220

http://www.w3.org/2001/XMLSchema#string