Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers - Wikidata - awgldk - TriplyDB

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

http://www.wikidata.org/entity/Q28214439

about

sameAs

Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance Chfr is linked to tumour metastasis through the downregulation of HDAC1 Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint Epigenetic inactivation of CHFR in human tumors Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells DNA demethylation caused by 5-Aza-2'-deoxycytidine induces mitotic alterations and aneuploidy Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers Chfr is required for tumor suppression and Aurora A regulation Safeguarding entry into mitosis: the antephase checkpoint.Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population.Epigenetic and genetic silencing of CHFR in esophageal adenocarcinomas.Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis.RNF8-dependent histone ubiquitination during DNA damage response and spermatogenesis Chfr and RNF8 synergistically regulate ATM activation.Regulation of the DNA damage response by ubiquitin conjugation.The auto-ubiquitylation of E3 ubiquitin-protein ligase Chfr at G2 phase is required for accumulation of polo-like kinase 1 and mitotic entry in mammalian cells.Gene-promoter hypermethylation as a biomarker in lung cancer.Throwing new light on lung cancer pathogenesis: updates on three recent topics.Applying whole-genome studies of epigenetic regulation to study human disease.CHFR is important for the first wave of ubiquitination at DNA damage sites Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia CHFR protein expression predicts outcomes to taxane-based first line therapy in metastatic NSCLC.CHFR: A Novel Mitotic Checkpoint Protein and Regulator of Tumorigenesis.Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with microsatellite instability in gastric cancer.Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine.CHFR: a key checkpoint component implicated in a wide range of cancers.Epigenetic Determinants of Cancer.Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma.CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.SNM1A acts downstream of ATM to promote the G1 cell cycle checkpoint Association between CHFR gene hypermethylation and gastric cancer risk: a meta-analysis Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR.Epigenetic silencing of checkpoint with fork-head associated and ring finger gene expression in esophageal cancer.Expression level of the mitotic checkpoint protein and G2-M cell cycle regulators and prognosis in gastrointestinal stromal tumors in the stomach.The diagnostic and prognostic value of CHFR hypermethylation in colorectal cancer, a meta-analysis and literature review.Clinicopathological significance of CHFR methylation in non-small cell lung cancer: a systematic review and meta-analysis.TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

P2860

Q24301653-6C779FBB-6327-49F6-829D-C5203008B872 Q24324032-7D28FBB6-7C45-4E63-B7A6-F8FD265EB282 Q24652321-3EE72B75-5FEE-4F0D-A15F-CFAB673B7093 Q24670147-2C480489-57EE-466F-9E8D-10A0AC5465D8 Q24676923-2B01432D-8A8E-4566-9322-9952981CC589 Q27339980-CA698244-9004-4B91-A410-F23D1BBAC065 Q27936398-5E0CD86D-69D4-4F6F-B38D-62233FC073CC Q28386334-E818E234-C286-4E2F-BC61-DDEA5D0E4549 Q28389551-1D01195A-441F-4421-B766-7DCFC0728709 Q28510913-1C0E4065-88E1-4325-ACE3-F346DD4FE120 Q33558235-294B007A-3DDD-4517-9237-D7F1E94DB8BE Q33887581-25E2D733-6FD6-4691-A0A1-6CEE76452862 Q34091569-1F0170F6-A816-454A-8909-FA79F8BB8721 Q34152941-BC0446D1-68FB-4E5B-BBB5-102952AEA1D9 Q34829400-0F9E6BAA-08F5-4B13-9FF7-C1C86431BE96 Q35089499-AFA10B01-709F-4871-949C-E8B8FFF2A441 Q35161624-3010CF45-E525-471A-80D4-FAADEDB962B3 Q35182916-56F65062-DA82-4F46-9AC8-055DD91A2BCA Q35877182-4108C674-292E-44CA-8F14-7B11373AD6E8 Q36050719-41A1A592-4D09-4809-8C7A-CAE7492A970E Q36485572-DDA4DC98-3EE7-4635-8591-34DBF9B8984E Q36580923-D7649F27-338D-41E4-969D-7E33F4AB5699 Q36694133-7E336D25-0AF0-4225-9758-0BC54EA86272 Q36698563-C288AF69-6F3D-40DF-B78A-B572D0A0E282 Q36831407-91C30DAE-4E6A-495B-8E79-7A04D58AE442 Q37203411-99FC2A9E-4BAF-40F9-901E-3C495E6BCCB6 Q37328459-6A3613E7-085C-424C-9DEE-9C0D5D165028 Q37705684-6190EAF4-6854-4E74-9363-AACEA7BB98E3 Q37967195-DC023498-D32D-4538-96D0-0F1F11374185 Q38837858-B03C9A72-CCCD-4B99-A702-03F313E56AB6 Q39485439-7F366359-512E-4291-B6FE-D2AE1E250EDB Q40448024-4B7C6F94-8F25-42A0-83DE-96E54715F4BF Q41660937-8AA9FC9D-11C9-4422-969F-ABAE7B473B50 Q41947888-E4E0DEA1-D503-4789-918F-014BB2DF1D2D Q42289696-704DCBDA-153A-4F40-8015-292D91FC7478 Q42801200-B41BC93C-E602-4695-8FD1-87EE9E101997 Q44522889-84327303-F783-4AEE-A13D-0022EB902917 Q47134227-F92927FC-DA38-4A65-8CD7-EC864306425D Q47193635-18C42D13-C026-4119-8E70-B6188FE5404E Q48247270-E92D89E4-4CEB-4135-9E63-C86D6CEAA820

P2860

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

http://www.wikidata.org/entity/Q28214439

description

2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2002

@ast

im April 2002 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: 4 April 2002)

@en

vedecký článok (publikovaný 2002/04/04)

@sk

vědecký článek publikovaný v roce 2002

@cs

wetenschappelijk artikel (gepubliceerd op 2002/04/04)

@nl

наукова стаття, опублікована у квітні 2002

@uk

مقالة علمية (نشرت في 4-4-2002)

@ar

name

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@ast

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@en

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@nl

type

label

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@ast

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@en

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@nl

prefLabel

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@ast

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@en

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@nl

P1433

Q28214439-25166D28-1401-41B3-A879-BAFB101B1DD5

P1476

Q28214439-D229A1D0-4222-477D-A498-2D127F8931AE

P2093

Q28214439-68770BD6-374F-443C-BE09-1C5AC6F28D0A

Q28214439-900EA443-2174-4885-8563-65E1CEBCA3F1

Q28214439-B06B159D-6032-4DF8-BD8E-36E8193F5A7C

Q28214439-B4266255-79FD-44FC-B621-A5A45C888A9A

Q28214439-BA79F24B-DC44-43EB-AB47-D82CC8C2D7B0

P2860

Q28214439-28856FEE-3CBB-4A2D-9701-E9F623AD46FD

Q28214439-2DAF555F-8E8F-4244-8B30-AA622AB01B3E

Q28214439-7143DDF2-7D38-474A-83E7-F9E6C1EF605F

Q28214439-814236C4-2343-4812-842D-C562F8AC1D7D

Q28214439-91F1C88D-2335-4F1D-BE13-77E078A03EA6

Q28214439-969B5173-FFA6-41E0-A4D1-309917824B82

Q28214439-9D95A3B1-B6EF-44A3-A153-382209F6AAF0

Q28214439-BCF5857F-3829-48FE-81D5-F7D8CA1DFDE0

Q28214439-D0BB97B0-2D0C-4AF0-B66D-B7B7CE617F5C

Q28214439-D7CD0B6C-CA8D-41FB-A864-86F6AC77F514

P2888

Q28214439-082FE04C-D2FB-4888-BC3D-054974CB82F8

P304

Q28214439-037D7F9F-DE1B-41AB-86AF-B17A7278D9DD

P31

Q28214439-D5B2E4BC-38A1-496D-A7ED-7A2ECF20B244

P356

Q28214439-213EF82F-F62E-44E5-B777-950A834D901F

P407

Q28214439-D2B1D7D1-3223-43DA-9DC2-E2E0BD696874

P433

Q28214439-25FAA2CE-9DCA-4A18-AF25-33E39B7B4D11

P478

Q28214439-3E74DB2F-3A40-4D05-94D8-AA0EAA1CFDD0

P50

Q28214439-02C8B48E-A7B7-44CB-B03C-0EC888E4D130

Q28214439-620EA716-6573-4CED-91A6-8CB9D2E809F8

Q28214439-EC1A9C20-1610-410E-B613-7B07F79DAE59

P577

Q28214439-C97A4D74-1776-49A9-9565-1B5B5433F9F9

P5875

Q28214439-D82B969F-426F-4BE9-B741-1E07C3D3CEC9

P6179

Q28214439-FE044B75-02C2-4852-A492-62A981022C65

P698

Q28214439-61AAFA7D-7E31-4EF1-8AED-22CB7AC86F24

P356

P1433

P1476

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

@en

P2093

Hirotaka Osada

http://www.w3.org/2001/XMLSchema#string

Kotaro Mizuno

http://www.w3.org/2001/XMLSchema#string

Tetsuya Mitsudomi

http://www.w3.org/2001/XMLSchema#string

Yoshio Tatematsu

http://www.w3.org/2001/XMLSchema#string

Yoshitaka Fujii

http://www.w3.org/2001/XMLSchema#string

P2860

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

p53, the cellular gatekeeper for growth and division

Cell cycle checkpoints: preventing an identity crisis

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

DNA hypermethylation in tumorigenesis: epigenetics joins genetics.

High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.

Somatic mutation of the hBUB1 mitotic checkpoint gene in primary lung cancer.

Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer.

P2888

P304

2328-2333

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1205402

http://www.w3.org/2001/XMLSchema#string

P407

P433

15

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P50

Takashi Takahashi

Hiroyuki Konishi

P577

2002-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11419044

http://www.w3.org/2001/XMLSchema#string

P6179

1039745972

http://www.w3.org/2001/XMLSchema#string

P698

11948416

http://www.w3.org/2001/XMLSchema#string