Pivalate-generating prodrugs and carnitine homeostasis in man
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A moderate excess of dietary lysine lowers plasma and tissue carnitine concentrations in pigs.PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis.Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats.Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women.Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis.Biosynthesis and metabolic pathways of pivalic acid.Role of carnitine in cancer chemotherapy-induced multiple organ toxicity.Emerging clinical role of pivmecillinam in the treatment of urinary tract infection in the context of multidrug-resistant bacteria.The use of mass spectrometry to analyze dried blood spots.An in vitro metabolomics approach to identify hepatotoxicity biomarkers in human L02 liver cells treated with pekinenal, a natural compound.Mitochondria as targets of drug toxicity: Lessons from the R118 phase I experience.In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094.Impact on L-carnitine Homeostasis of Short-term Treatment with the Pivalate Prodrug Tenofovir Dipivoxil.Synthesis and anti-herpetic activity of phosphoramidate ProTides.Primary carnitine deficiency and pivalic acid exposure causing encephalopathy and fatal cardiac events.A Moderate Carnitine Deficiency Exacerbates Isoproterenol-Induced Myocardial Injury in Rats.Determination of carnitine ester patterns during the second half of pregnancy, at delivery, and in neonatal cord blood by tandem mass spectrometry: complex and dynamic involvement of carnitine in the intermediary metabolism.Role of carnitine and its derivatives in the development and management of type 2 diabetes.Effects of fish oil and conjugated linoleic acids on carnitine homeostasis in laying hens.
P2860
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P2860
Pivalate-generating prodrugs and carnitine homeostasis in man
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Pivalate-generating prodrugs and carnitine homeostasis in man
@ast
Pivalate-generating prodrugs and carnitine homeostasis in man
@en
Pivalate-generating prodrugs and carnitine homeostasis in man
@nl
type
label
Pivalate-generating prodrugs and carnitine homeostasis in man
@ast
Pivalate-generating prodrugs and carnitine homeostasis in man
@en
Pivalate-generating prodrugs and carnitine homeostasis in man
@nl
prefLabel
Pivalate-generating prodrugs and carnitine homeostasis in man
@ast
Pivalate-generating prodrugs and carnitine homeostasis in man
@en
Pivalate-generating prodrugs and carnitine homeostasis in man
@nl
P356
P1476
Pivalate-generating prodrugs and carnitine homeostasis in man
@en
P2093
Eric P Brass
P304
P356
10.1124/PR.54.4.589
P407
P577
2002-12-01T00:00:00Z