Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
about
sameAs
A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombinationDiversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesisThe molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersThe syndrome of 17,20 lyase deficiencyA PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replicationRegulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17Heterogeneous nuclear ribonucleoprotein A2 is a SET-binding protein and a PP2A inhibitor.Proteomic analysis of SET-binding proteins.Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a.Adrenarche - physiology, biochemistry and human disease.Expression of the SET protein in testes of mice at different developmental stages.Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5.Approach to the girl with early onset of pubic hair.Protein phosphatase 2A activity affects histone H3 phosphorylation and transcription in Drosophila melanogaster.Expression of P450c17 in the human fetal nervous system.P450 oxidoreductase deficiency: a new disorder of steroidogenesis.Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations.Pathways leading to phosphorylation of p450c17 and to the posttranslational regulation of androgen biosynthesisSET protein up-regulated testosterone production in the cultured preantral follicles.Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition.Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase.Homozygous mutation G539R in the gene for P450 oxidoreductase in a family previously diagnosed as having 17,20-lyase deficiency.Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome.Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical implications.Phosphorylation of human cytochrome P450c17 by p38α selectively increases 17,20 lyase activity and androgen biosynthesis.Nonhuman primates as models for human adrenal androgen production: function and dysfunction.Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice.Complex assembly on the human CYP17 promoter.Clinical, genetic, and enzymatic characterization of P450 oxidoreductase deficiency in four patients.Post-translational dual regulation of cytochrome P450 aromatase at the catalytic and protein levels by phosphorylation/dephosphorylation.A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signalingTargeting inhibitor 2 of protein phosphatase 2A as a therapeutic strategy for prostate cancer treatment.Inhibition of protein phosphatase 2A activity by PI3Kγ regulates β-adrenergic receptor function.Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) isoforms.Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells.Isolation of marmoset P450c17 cDNA and gene regulation in vitro.P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes.The SET protein promotes androgen production in testicular Leydig cells.Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.
P2860
Q24299264-B7E2DB70-FF97-46E1-BDD8-97AD0CECBCECQ24531477-02159401-27B0-4B34-82EB-1548C78856B3Q24613957-FA660BAE-4E99-4161-893F-CECE3F4E13DEQ24614420-2F897DB8-D07C-47B6-8BF1-95B12999F8A2Q24626425-750F7D33-74C5-4E60-A892-3C1D27BEA45EQ28305458-A8ED81D3-7238-47AC-8423-D8B4309825ABQ33223554-6631D43F-151F-41EB-9C08-78D68FEA8C13Q33274521-38F10C97-5106-4894-B7F3-D32E519C0C99Q33772407-67BD5629-703D-4D8C-A113-C8B1D399F472Q34304054-D7C1804D-7D73-44CE-B5D1-E678BD013733Q34433188-54A88022-56D5-4A5C-9AA2-C35E627C779BQ34806402-6B8A3DB6-6C5E-4E86-96FA-A818A97AF5A9Q35001879-BB81483E-190E-4E94-A7B9-1ABB09856853Q35661433-CA4AEC4B-7254-4266-B718-27B4F432FCF8Q35920716-11296AFE-5B9C-4973-A280-C1CF5D89AA73Q36391566-096B22E2-1865-4F47-9E57-E9A223052ECCQ36446526-C8FB41A1-CF32-401E-B662-05E475ABF402Q36578772-8097B6FA-FB66-4F78-B736-1B4129BF02B8Q36643376-F77F5E13-5DD4-4D67-9789-DF384C2F1D9DQ36837717-ECDC511B-6867-43A5-B0B1-E2BC4B84298BQ36884023-38CD80A6-2DAE-4E6F-8B57-3527061E4B07Q36938329-62BB6B85-39FD-4E91-9DEA-98CEE3BF18A7Q36939082-BD1DC769-F9D7-44D5-A0D5-048D263975E3Q37071255-5ACA0C24-07FD-4B66-826B-E70EC5092BF0Q37099736-DEDADDF7-BE41-4583-AC61-C74EF8F15FDEQ37122965-82AA5747-0EE2-43C9-A5F7-3C084DBB23FFQ37143613-94791EAA-F3F6-4FD8-B0FC-740D14410404Q37325136-ED85D2AD-EBEA-4883-999A-7FD247F56E51Q37482676-C1C5DD21-07A0-4BFE-899F-EE7748A43A37Q38962666-03C37C12-AC70-4443-91C9-7AA5B03D659FQ38986420-DB07C34A-0EEE-4570-9C9C-4AEAF1F57EDAQ39097201-0711FCE5-F265-436D-8649-BBDB9A988EA5Q42703429-B9AA780D-F036-48CC-B9F3-963BB00ACBEDQ43931376-2307082F-C589-4E0B-B5AB-02B06AC6E3CEQ44547316-744E8335-A757-49DA-A2C8-4C3CE5A49017Q45235683-E289A385-1A9A-4311-AD99-DEDB89D69518Q46458848-E9F70144-F2A9-4850-8C2F-4F77942C525AQ51767184-F78051A8-942D-40B4-9E63-76DAAA47F680Q55638445-BC525DE0-23AC-426C-9FE0-C7472B2BE66C
P2860
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@ast
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@en
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@nl
type
label
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@ast
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@en
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@nl
prefLabel
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@ast
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@en
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@nl
P2860
P356
P1476
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17
@en
P2093
Synthia H Mellon
Walter L Miller
P2860
P304
P356
10.1074/JBC.M209527200
P407
P577
2003-01-31T00:00:00Z