Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms - Wikidata - awgldk - TriplyDB

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

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WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis Molecular regulation of NKCC2 in the thick ascending limb Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion Thick ascending limb: the Na(+):K (+):2Cl (-) co-transporter, NKCC2, and the calcium-sensing receptor, CaSR Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells Activity of the renal Na+-K+-2Cl- cotransporter is reduced by mutagenesis of N-glycosylation sites: role for protein surface charge in Cl- transport Affinity-defining domains in the Na-Cl cotransporter: a different location for Cl- and thiazide binding A mathematical model of rat ascending Henle limb. I. Cotransporter function Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.Ammonium transport and pH regulation by K(+)-Cl(-) cotransporters.Antihypertensive medications, bone mineral density, and fractures: a review of old cardiac drugs that provides new insights into osteoporosis.Molecular mechanisms of cation transport by the renal Na+-K+-Cl- cotransporter: structural insight into the operating characteristics of the ion transport sites.The Na+-K+-2Cl- cotransporter and the osmotic stress response in a model salt transport epithelium.Rare mutations in the human Na-K-Cl cotransporter (NKCC2) associated with lower blood pressure exhibit impaired processing and transport function.Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension Structure-activity relationships of bumetanide derivatives: correlation between diuretic activity in dogs and inhibition of the human NKCC2A transporter Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain.Novel insights regarding the operational characteristics and teleological purpose of the renal Na+-K+-Cl2 cotransporter (NKCC2s) splice variants.Transport efficiency and workload distribution in a mathematical model of the thick ascending limb.Fluid dilution and efficiency of Na(+) transport in a mathematical model of a thick ascending limb cell.Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.Salt-sensing mechanisms in blood pressure regulation and hypertension.Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance.Parameter estimation for mathematical models of NKCC2 cotransporter isoforms.Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominant-negative effect of the AF splice variant.Independent regulation of Na+ and K+ balance by the kidney.Chloride transport.Physiology and pathophysiology of the renal Na-K-2Cl cotransporter (NKCC2).Functional consequences of NKCC2 splice isoforms: insights from a Xenopus oocyte model.Physiological role of SLC12 family members in the kidney.The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl- absorption, via basolateral KCC1, and reduces fluid loss.Functional and molecular characterization of the shark renal Na-K-Cl cotransporter: novel aspects.The potassium chloride cotransporter KCC-2 coordinates development of inhibitory neurotransmission and synapse structure in Caenorhabditis elegans.Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.A mathematical model of rat ascending Henle limb. II. Epithelial function.Angiotensin II and renal medullary blood flow in Lyon rats.

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P2860

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

http://www.wikidata.org/entity/Q28215518

description

2002 nî lūn-bûn

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2002 թուականի Մարտին հրատարակուած գիտական յօդուած

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2002 թվականի մարտին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@ast

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@en

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@nl

type

label

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@ast

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@en

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@nl

prefLabel

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@ast

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@en

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms

@en

P2093

Norma Vazquez

http://www.w3.org/2001/XMLSchema#string

Patricia Meade

http://www.w3.org/2001/XMLSchema#string

Steven C Hebert

http://www.w3.org/2001/XMLSchema#string

P2860

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2

The role of transmembrane domain 2 in cation transport by the Na-K-Cl cotransporter.

Uncompensated polyuria in a mouse model of Bartter's syndrome

Protein kinase C activation reduces the function of the Na(+):K(+):2Cl(-) cotransporter in Xenopus laevis oocytes.

Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.

Electroneutral chloride-coupled co-transporters.

Sodium chloride and water transport in the medullary thick ascending limb of Henle. Evidence for active chloride transport

Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney.

Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter.

Mutagenic mapping of the Na-K-Cl cotransporter for domains involved in ion transport and bumetanide binding.

P304

11004-11012

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scholarly article

P356

10.1074/JBC.M110442200

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P407

P433

13

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P478

277

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P50

P577

2002-01-14T00:00:00Z

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P698

11790783

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