The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
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The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawalMammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasisTHAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell deathIdentification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTSIdentification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinaseOmi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosisMolecular crosstalk between apoptosis, necroptosis, and survival signalingChondrocyte Apoptosis in the Pathogenesis of OsteoarthritisRegulation of Cell Death by IAPs and Their AntagonistsSmall-molecule SMAC mimetics as new cancer therapeuticsApoptosis and autophagy induction as mechanism of cancer prevention by naturally occurring dietary agentsConservation of hearing and protection of hair cells in cochlear implant patients' with residual hearingStructural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domainInsights on Molecular Mechanisms of Chondrocytes Death in OsteoarthritisInhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding proteinDistribution of the serine protease HtrA1 in normal human tissuesThe mitochondrial serine protease HtrA2/Omi: an overviewOmi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15Apoptosis: a review of programmed cell deathMechanism of the interaction between the intrinsically disordered C-terminus of the pro-apoptotic ARTS protein and the Bir3 domain of XIAPAberrant Apoptotic Response of Colorectal Cancer Cells to Novel Nucleoside AnaloguesDrosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from ParkinMolecular mechanisms of caspase regulation during apoptosisCaspase- and serine protease-dependent apoptosis by the death domain of FADD in normal epithelial cells.Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration.Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.Microarray data analysis of mouse neoplasia.HtrA2/Omi terminates cytomegalovirus infection and is controlled by the viral mitochondrial inhibitor of apoptosis (vMIA)Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders.Mitochondrial quality control: insights on how Parkinson's disease related genes PINK1, parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis.Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell deathCytokine-induced tumor suppressors: a GRIM storyProgrammed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila.Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases.Participation of Omi Htra2 serine-protease activity in the apoptosis induced by cisplatin on SW480 colon cancer cells.The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.Regulation of apoptosis by ubiquitination.Pathways involved in interleukin-1β-mediated murine cardiomyocyte apoptosis.
P2860
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P2860
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
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2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@ast
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@en
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@nl
type
label
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@ast
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@en
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@nl
prefLabel
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@ast
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@en
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@nl
P2093
P2860
P356
P1476
The serine protease Omi/HtrA2 ...... uces enhanced caspase activity
@en
P2093
Alnemri ES
Declercq W
Srinivasula SM
Vandekerckhove J
van Gurp M
P2860
P2888
P356
10.1038/SJ.CDD.4400970
P407
P577
2002-01-01T00:00:00Z