Inhaled P2Y2 receptor agonists as a treatment for patients with Cystic Fibrosis lung disease
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International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyDevelopment of a novel transgenic rat overexpressing the P2Y(2) nucleotide receptor using a lentiviral vectorPharmacological characterisation of the adenosine receptor mediating increased ion transport in the mouse isolated trachea and the effect of allergen challengeP2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.Coupling of P2Y receptors to G proteins and other signaling pathwaysPharmacological approaches to correcting the ion transport defect in cystic fibrosis.Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues.UTP activates small-conductance Ca2+-activated K+ channels in murine detrusor PDGFRα+ cellsMolecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.E-NTPDases in human airways: Regulation and relevance for chronic lung diseasesRole of mechanical stress in regulating airway surface hydration and mucus clearance ratesExtracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targetsUTP regulation of ion transport in alveolar epithelial cells involves distinct mechanisms.Dimerization of G protein-coupled purinergic receptors: increasing the diversity of purinergic receptor signal responses and receptor functions.Challenges and advances in the development of inhalable drug formulations for cystic fibrosis lung disease.The discovery of a new class of synaptic transmitters in smooth muscle 50 years ago and amelioration of coronary artery thrombosis.Extracellular alkalinization stimulates calcium-activated chloride conductance in cystic fibrosis human airway epithelial cells.A P2X ion channel-triggered NF-kappaB pathway enhances TNF-alpha-induced IL-8 expression in airway epithelial cells.Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner.Extracellular zinc and ATP restore chloride secretion across cystic fibrosis airway epithelia by triggering calcium entry.MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology.P2Y2 receptor binds ATP and UTPPhase 2 randomized safety and efficacy trial of nebulized denufosol tetrasodium in cystic fibrosis.
P2860
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P2860
Inhaled P2Y2 receptor agonists as a treatment for patients with Cystic Fibrosis lung disease
description
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Dezember 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 5 December 2002)
@en
vedecký článok (publikovaný 2002/12/05)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/12/05)
@nl
наукова стаття, опублікована в грудні 2002
@uk
مقالة علمية (نشرت في 5-12-2002)
@ar
name
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@ast
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@en
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@nl
type
label
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@ast
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@en
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@nl
prefLabel
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@ast
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@en
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@nl
P2093
P1476
Inhaled P2Y2 receptor agonists ...... h Cystic Fibrosis lung disease
@en
P2093
Christy Shaffer
Dave Mathews
Don Kellerman
Richard Evans
P304
P356
10.1016/S0169-409X(02)00154-0
P407
P577
2002-12-05T00:00:00Z