The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review)
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A novel class of ligand-gated ion channel is activated by Zn2+Detection of human and rodent 5-HT3B receptor subunits by anti-peptide polyclonal antibodiesExamination of association of genes in the serotonin system to autism5-HT3 receptorsHigh-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptorThe 5-HT3 receptor as a therapeutic targetSerotonin as a New Therapeutic Target for Diabetes Mellitus and ObesityMarine Toxins Targeting Ion ChannelsMechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.Kinetics of anesthetic-induced conformational transitions in a four-alpha-helix bundle protein.Agonists and antagonists bind to an A-A interface in the heteromeric 5-HT3AB receptor.Mapping spatial relationships between residues in the ligand-binding domain of the 5-HT3 receptor using a molecular rulerHomology modeling and molecular dynamics simulations of the glycine receptor ligand binding domainHigh-affinity fluorescent ligands for the 5-HT(3) receptorCrystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.Structural answers and persistent questions about how nicotinic receptors work.Investigation of HTR3C mutations for association with 5HT(3) receptor antagonist anti-emetic efficacy.5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals.Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor.Molecular properties important for inhaled anesthetic action on human 5-HT3A receptors.Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols.The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors.A comparison of the pharmacological properties of guinea-pig and human recombinant 5-HT4 receptors.5-HT(3) receptors.The frequency of calcium oscillations induced by 5-HT, ACH, and KCl determine the contraction of smooth muscle cells of intrapulmonary bronchioles.Modulating inhibitory ligand-gated ion channels.The L293 residue in transmembrane domain 2 of the 5-HT3A receptor is a molecular determinant of allosteric modulation by 5-hydroxyindole.Pruritus and fatigue associated with liver disease: is there a role for ondansetron?5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function.Genotype frequencies for polymorphisms related to chemotherapy-induced nausea and vomiting in a Japanese population.Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor.Structural model of rho1 GABAC receptor based on evolutionary analysis: Testing of predicted protein-protein interactions involved in receptor assembly and function.The structural basis of function in Cys-loop receptors.The in vivo neurochemistry of the brain during general anesthesia.Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT3AB receptors.Influence of sodium substitutes on 5-HT-mediated effects at mouse 5-HT3 receptors.Toward biophysical probes for the 5-HT3 receptor: structure-activity relationship study of granisetron derivatives.Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.Pores formed by the nicotinic receptor m2delta Peptide: a molecular dynamics simulation study.Co-expression of the 5-HT3B serotonin receptor subunit alters the biophysics of the 5-HT3 receptor.
P2860
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P2860
The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review)
description
2002 nî lūn-bûn
@nan
2002 թուականին հրատարակուած գիտական յօդուած
@hyw
2002 թվականին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The molecular basis of the str ...... and-gated ion channel (review)
@ast
The molecular basis of the str ...... and-gated ion channel (review)
@en
The molecular basis of the str ...... and-gated ion channel (review)
@nl
type
label
The molecular basis of the str ...... and-gated ion channel (review)
@ast
The molecular basis of the str ...... and-gated ion channel (review)
@en
The molecular basis of the str ...... and-gated ion channel (review)
@nl
prefLabel
The molecular basis of the str ...... and-gated ion channel (review)
@ast
The molecular basis of the str ...... and-gated ion channel (review)
@en
The molecular basis of the str ...... and-gated ion channel (review)
@nl
P3181
P1476
The molecular basis of the str ...... and-gated ion channel (review)
@en
P2093
David C Reeves
Sarah C R Lummis
P3181
P356
10.1080/09687680110110048
P407
P577
2002-01-01T00:00:00Z