Gamma protocadherins are required for survival of spinal interneurons
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Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contactComparative genomics and diversifying selection of the clustered vertebrate protocadherin genesMultiple variable first exons: a mechanism for cell- and tissue-specific gene regulationSynaptic cell adhesionAkirin2 is essential for the formation of the cerebral cortexPostsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous systemFunctional significance of isoform diversification in the protocadherin gamma gene clusterPhosphorylation of protocadherin proteins by the receptor tyrosine kinase RetCombinatorial homophilic interaction between gamma-protocadherin multimers greatly expands the molecular diversity of cell adhesionProteolytic processing of protocadherin proteins requires endocytosisClustered protocadherinsCombinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processingGamma-protocadherin homophilic interaction and intracellular trafficking is controlled by the cytoplasmic domain in neuronsProtocadherin α (PCDHA) as a novel susceptibility gene for autismA variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathwayGamma protocadherins are required for synaptic development in the spinal cordThe b1 isoform of protocadherin-gamma (Pcdhgamma) interacts with the microtubule-destabilizing protein SCG10Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomesA differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene clusterInteraction with protocadherin-gamma regulates the cell surface expression of protocadherin-alphagamma-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retinaCoelacanth genome sequence reveals the evolutionary history of vertebrate genesStructure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic SpecificityAntiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4Structural elements necessary for oligomerization, trafficking, and cell sorting function of paraxial protocadherin.γ-protocadherins are enriched and transported in specialized vesicles associated with the secretory pathway in neuronsDistinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon TargetingClustered Protocadherins Are Required for Building Functional Neural Circuits.Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.Genetics and cell biology of building specific synaptic connectivity.Identification and comparative analysis of the protocadherin cluster in a reptile, the green anole lizard.Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Pcdha cluster.Proteomics analysis reveals overlapping functions of clustered protocadherins.High frequency of rare variants with a moderate-to-high predicted biological effect in protocadherin genes of extremely obeseGamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice.Biography of Joshua R. Sanes.LC3-dependent intracellular membrane tubules induced by gamma-protocadherins A3 and B2: a role for intraluminal interactions.Increasing the specificity of neurotrophic factors.Regulation of protocadherin gene expression by multiple neuron-restrictive silencer elements scattered in the gene cluster.Evolution of orthologous tandemly arrayed gene clusters.
P2860
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P2860
Gamma protocadherins are required for survival of spinal interneurons
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Gamma protocadherins are required for survival of spinal interneurons
@ast
Gamma protocadherins are required for survival of spinal interneurons
@en
Gamma protocadherins are required for survival of spinal interneurons
@nl
type
label
Gamma protocadherins are required for survival of spinal interneurons
@ast
Gamma protocadherins are required for survival of spinal interneurons
@en
Gamma protocadherins are required for survival of spinal interneurons
@nl
prefLabel
Gamma protocadherins are required for survival of spinal interneurons
@ast
Gamma protocadherins are required for survival of spinal interneurons
@en
Gamma protocadherins are required for survival of spinal interneurons
@nl
P2093
P3181
P1433
P1476
Gamma protocadherins are required for survival of spinal interneurons
@en
P2093
Allan Bradley
Ann Marie Craig
Joshua R Sanes
Sabine Levi
Xiaozhong Wang
P304
P3181
P356
10.1016/S0896-6273(02)01090-5
P407
P577
2002-12-01T00:00:00Z