A single transmembrane site in the KCNE-encoded proteins controls the specificity of KvLQT1 channel gating
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Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillationAnalysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunitsGain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillationInteraction of KCNE subunits with the KCNQ1 K+ channel poreKCNQ1 channel modulation by KCNE proteins via the voltage-sensing domainStructure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel † ‡KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channelStructural basis of slow activation gating in the cardiac I Ks channel complexPreparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndromeKCNE2 and the K (+) channel: the tail wagging the dogA shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensorFunctional delivery of a membrane protein into oocyte membranes using bicellesSexual dimorphism and oestrogen regulation of KCNE3 expression modulates the functional properties of KCNQ1 K⁺ channelsWorking model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel.Functional interactions between KCNE1 C-terminus and the KCNQ1 channel.Mechanisms of disease pathogenesis in long QT syndrome type 5N-terminal arginines modulate plasma-membrane localization of Kv7.1/KCNE1 channel complexes.KCNE4 juxtamembrane region is required for interaction with calmodulin and for functional suppression of KCNQ1.The KCNQ1 potassium channel: from gene to physiological function.KCNQ1/KCNE1 assembly, co-translation not required.KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environmentsRegulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Molecular mechanisms underlying KVS-1-MPS-1 complex assembly.The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes.KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains.Voltage-dependent C-type inactivation in a constitutively open K+ channelKCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulationModification of K+ channel-drug interactions by ancillary subunits.Building KCNQ1/KCNE1 channel models and probing their interactions by molecular-dynamics simulations.The KCNE Tango - How KCNE1 Interacts with Kv7.1.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.Cardiac Delayed Rectifier Potassium Channels in Health and Disease.Chansporter complexes in cell signaling.A new KCNQ1 mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome.Association of KCNE1 genetic polymorphisms with atrial fibrillation in a Chinese Han population.KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels.Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel.Role of the S6 C-terminus in KCNQ1 channel gating.
P2860
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P2860
A single transmembrane site in the KCNE-encoded proteins controls the specificity of KvLQT1 channel gating
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A single transmembrane site in ...... icity of KvLQT1 channel gating
@ast
A single transmembrane site in ...... icity of KvLQT1 channel gating
@en
A single transmembrane site in ...... icity of KvLQT1 channel gating
@nl
type
label
A single transmembrane site in ...... icity of KvLQT1 channel gating
@ast
A single transmembrane site in ...... icity of KvLQT1 channel gating
@en
A single transmembrane site in ...... icity of KvLQT1 channel gating
@nl
prefLabel
A single transmembrane site in ...... icity of KvLQT1 channel gating
@ast
A single transmembrane site in ...... icity of KvLQT1 channel gating
@en
A single transmembrane site in ...... icity of KvLQT1 channel gating
@nl
P2093
P356
P1476
A single transmembrane site in ...... icity of KvLQT1 channel gating
@en
P2093
Andrew Krumerman
Thomas V McDonald
Yonathan F Melman
P304
P356
10.1074/JBC.M200564200
P407
P577
2002-07-12T00:00:00Z