The calicheamicin gene cluster and its iterative type I enediyne PKS
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Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesisBiochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesisPolyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynesComplete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificityBiosynthesis and function of polyacetylenes and allied natural productsThe structural biology of enzymes involved in natural product glycosylationStructural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathwayStructure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne BiosynthesisMolecular Basis of Substrate Promiscuity for the SAM-Dependent O -Methyltransferase NcsB1, Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic NeocarzinostatinStructural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathwaySolution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesisCrystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne BiosynthesisStructure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinosporaEnzymatic methods for glyco(diversification/randomization) of drugs and small moleculesThe TetR family of transcriptional repressors.Towards prediction of metabolic products of polyketide synthases: an in silico analysisAncient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungiWidespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine spongesStrain Prioritization and Genome Mining for Enediyne Natural ProductsNatural-product sugar biosynthesis and enzymatic glycodiversification.Cloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in "Streptomyces carzinostaticus"Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner.Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways.A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.Cyclization of aromatic polyketides from bacteria and fungiCharacterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6.Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulansNatural products version 2.0: connecting genes to molecules.Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.Engineering polyketide synthases and nonribosomal peptide synthetases.An in planta-expressed polyketide synthase produces (R)-mellein in the wheat pathogen Parastagonospora nodorumThe biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710Glycosyloxyamine neoglycosylation: a model study using calicheamicin.Polyketide and non-ribosomal peptide synthases: falling together by coming apart.Biosynthesis of enediyne antitumor antibioticsBiosynthetic genes and activity spectrum of antifungal polyynes from Collimonas fungivorans Ter331.Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase
P2860
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P2860
The calicheamicin gene cluster and its iterative type I enediyne PKS
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The calicheamicin gene cluster and its iterative type I enediyne PKS
@ast
The calicheamicin gene cluster and its iterative type I enediyne PKS
@en
The calicheamicin gene cluster and its iterative type I enediyne PKS
@nl
type
label
The calicheamicin gene cluster and its iterative type I enediyne PKS
@ast
The calicheamicin gene cluster and its iterative type I enediyne PKS
@en
The calicheamicin gene cluster and its iterative type I enediyne PKS
@nl
prefLabel
The calicheamicin gene cluster and its iterative type I enediyne PKS
@ast
The calicheamicin gene cluster and its iterative type I enediyne PKS
@en
The calicheamicin gene cluster and its iterative type I enediyne PKS
@nl
P2093
P3181
P356
P1433
P1476
The calicheamicin gene cluster and its iterative type I enediyne PKS
@en
P2093
Alfredo Staffa
Anne Czisny
Brian O Bachmann
Chris M Farnet
Emmanuel Zazopoulos
Erica Shepard
Joachim Ahlert
Jon S Thorson
Kexue Huang
Leonid Fonstein
P304
P3181
P356
10.1126/SCIENCE.1072105
P407
P577
2002-08-16T00:00:00Z