Structure-function analysis of human triacylglycerol hydrolase by site-directed mutagenesis: identification of the catalytic triad and a glycosylation site
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The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humansN-acetylanthranilate amidase from Arthrobacter nitroguajacolicus Rü61a, an alpha/beta-hydrolase-fold protein active towards aryl-acylamides and -esters, and properties of its cysteine-deficient variant.Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingComparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signalingGenomic structure and transcriptional regulation of the rat, mouse, and human carboxylesterase genes.Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs.Proteomics in the genome engineering era.Carboxylesterases in lipid metabolism: from mouse to human.Mutation of F417 but not of L418 or L420 in the lipid binding domain decreases the activity of triacylglycerol hydrolase.Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates.Attenuation of adipocyte triacylglycerol hydrolase activity decreases basal fatty acid efflux.
P2860
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P2860
Structure-function analysis of human triacylglycerol hydrolase by site-directed mutagenesis: identification of the catalytic triad and a glycosylation site
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structure-function analysis of ...... triad and a glycosylation site
@ast
Structure-function analysis of ...... triad and a glycosylation site
@en
Structure-function analysis of ...... triad and a glycosylation site
@nl
type
label
Structure-function analysis of ...... triad and a glycosylation site
@ast
Structure-function analysis of ...... triad and a glycosylation site
@en
Structure-function analysis of ...... triad and a glycosylation site
@nl
prefLabel
Structure-function analysis of ...... triad and a glycosylation site
@ast
Structure-function analysis of ...... triad and a glycosylation site
@en
Structure-function analysis of ...... triad and a glycosylation site
@nl
P2093
P356
P1433
P1476
Structure-function analysis of ...... triad and a glycosylation site
@en
P2093
Dennis E Vance
Mustafa Alam
Richard Lehner
P304
P356
10.1021/BI0255625
P407
P577
2002-05-28T00:00:00Z