The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission - Wikidata - awgldk - TriplyDB

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

http://www.wikidata.org/entity/Q28235694

about

C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization Metabolic regulation of mitochondrial dynamics Alterations in Mitochondrial Quality Control in Alzheimer's Disease Mitochondrial Quality Control and Muscle Mass Maintenance Applications of phototransformable fluorescent proteins for tracking the dynamics of cellular components Mitochondrial protein quality control: the mechanisms guarding mitochondrial health Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice Ceramide induced mitophagy and tumor suppression Mitochondrial division and fusion in metabolism Mitochondrial dynamics in diabetic cardiomyopathy The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane.PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease.Multifunctional Mitochondrial AAA Proteases Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division.Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system.Novel roles for actin in mitochondrial fission Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver.Shaping the dynamic mitochondrial network Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.Mitochondrial Diseases Part II: Mouse models of OXPHOS deficiencies caused by defects in regulatory factors and other components required for mitochondrial function.Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models.Stoichiometric expression of mtHsp40 and mtHsp70 modulates mitochondrial morphology and cristae structure via Opa1L cleavage.Photoactivatable green fluorescent protein-based visualization and quantification of mitochondrial fusion and mitochondrial network complexity in living cells.Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.Loss of Drosophila i-AAA protease, dYME1L, causes abnormal mitochondria and apoptotic degeneration.Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy.L-OPA1 regulates mitoflash biogenesis independently from membrane fusion.Novel regulatory roles of Mff and Drp1 in E3 ubiquitin ligase MARCH5-dependent degradation of MiD49 and Mcl1 and control of mitochondrial dynamics.A threshold of transmembrane potential is required for mitochondrial dynamic balance mediated by DRP1 and OMA1.Janus-faces of NME-oncoprotein interactions.

P2860

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P2860

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

http://www.wikidata.org/entity/Q28235694

description

2014 nî lūn-bûn

@nan

2014 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@ast

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@en

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@nl

type

label

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@ast

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@en

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@nl

prefLabel

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@ast

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@en

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@nl

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P2860

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P3181

P356

P1433

Journal of Cell Biology

P1476

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

@en

P2093

Astrid C Schauss

http://www.w3.org/2001/XMLSchema#string

Michael J Baker

http://www.w3.org/2001/XMLSchema#string

Nikolay Kladt

http://www.w3.org/2001/XMLSchema#string

Thomas Langer

http://www.w3.org/2001/XMLSchema#string

P2860

NIH Image to ImageJ: 25 years of image analysis

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

MiD49 and MiD51, new components of the mitochondrial fission machinery.

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

P304

919-29

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2779802

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P356

10.1083/JCB.201308006

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P407

P433

6

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P478

204

http://www.w3.org/2001/XMLSchema#string

P50

Elena I Rugarli

P577

2014-03-17T00:00:00Z

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260684523

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P698

24616225

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P932

3998800

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