DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion
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Munc18-syntaxin complexes and exocytosis in human plateletsA role for Sec1/Munc18 proteins in platelet exocytosisMunc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactionsDoc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter releaseDOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytesDOC2B acts as a calcium switch and enhances vesicle fusionCast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1Role of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter release processSynaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter releaseMolecular interactions position Mso1p, a novel PTB domain homologue, in the interface of the exocyst complex and the exocytic SNARE machinery in yeast.The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis.Sec1p binds to SNARE complexes and concentrates at sites of secretionAnalysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endingsRegulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18Subunit heterogeneity of cytoplasmic dynein: Differential expression of 14 kDa dynein light chains in rat hippocampusMunc18c depletion selectively impairs the sustained phase of insulin releaseTransient, phorbol ester-induced DOC2-Munc13 interactions in vivoDevelopment of the mouse hypothalamo-neurohypophysial system in the munc18-1 null mutant that lacks regulated secretionDifferent spatiotemporal expression of DOC2 genes in the developing rat brain argues for an additional, nonsynaptic role of DOC2B in early developmentInteraction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transportMunc-18-1 inhibits phospholipase D activity by direct interaction in an epidermal growth factor-reversible manner.Integrated protein array screening and high throughput validation of 70 novel neural calmodulin-binding proteinsProtein-protein interactions and protein modules in the control of neurotransmitter release.Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4Doc2b enrichment enhances glucose homeostasis in mice via potentiation of insulin secretion and peripheral insulin sensitivityMunc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells.Gene regulation in the magnocellular hypothalamo-neurohypophysial system.Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles.Insight into the role of Ca2+-binding protein 5 in vesicle exocytosis.Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery.Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis.The functions of Munc18-1 in regulated exocytosis.Miller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse.Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cellsGelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis.Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoformsDirect quantitative detection of Doc2b-induced hemifusion in optically trapped membranesDoc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity
P2860
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P2860
DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion
description
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
im März 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: March 1997)
@en
vedecký článok (publikovaný 1997-03)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd in 1997-03)
@nl
наукова стаття, опублікована в березні 1997
@uk
научни чланак (објављен 1997-03)
@sr
name
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@ast
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@en
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@nl
type
label
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@ast
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@en
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@nl
prefLabel
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@ast
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@en
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@nl
P2093
P1433
P1476
DOC2 proteins in rat brain: co ...... s in early stages of secretion
@en
P2093
J P Burbach
K J de Vries
W H Gispen
P304
P356
10.1016/S0896-6273(00)81245-3
P407
P577
1997-03-01T00:00:00Z