Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors
about
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsSuppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels.Enabling functional genomics with genome engineeringTargeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked BehaviorInduction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library.Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coliModular system for the construction of zinc-finger libraries and proteins.Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNAUpregulating endogenous genes by an RNA-programmable artificial transactivator.New strategies for cardiovascular gene therapy: regulatable pre-emptive expression of pro-angiogenic and antioxidant genesTranscriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo.Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domainDesign and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus.Transduction of artificial transcriptional regulatory proteins into human cellsRNA activation of haploinsufficient Foxg1 gene in murine neocortex.Regulation of the endogenous VEGF-A gene by exogenous designed regulatory proteins.Small-molecule regulators that mimic transcription factorsDrugging the undruggable: transcription therapy for cancer.Advanced Gene Manipulation Methods for Stem Cell Theranostics.Engineered zinc-finger transcription factors activate OCT4 (POU5F1), SOX2, KLF4, c-MYC (MYC) and miR302/367.microRNA-100 targets SMRT/NCOR2, reduces proliferation, and improves survival in glioblastoma animal models.From Bioengineering to CRISPR/Cas9 - A Personal Retrospective of 20 Years of Research in Programmable Genome Targeting.Neuroepigenetic Editing.
P2860
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P2860
Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Repression of vascular endothe ...... c finger transcription factors
@ast
Repression of vascular endothe ...... c finger transcription factors
@en
Repression of vascular endothe ...... c finger transcription factors
@nl
type
label
Repression of vascular endothe ...... c finger transcription factors
@ast
Repression of vascular endothe ...... c finger transcription factors
@en
Repression of vascular endothe ...... c finger transcription factors
@nl
prefLabel
Repression of vascular endothe ...... c finger transcription factors
@ast
Repression of vascular endothe ...... c finger transcription factors
@en
Repression of vascular endothe ...... c finger transcription factors
@nl
P2093
P1433
P1476
Repression of vascular endothe ...... c finger transcription factors
@en
P2093
Alan P Wolffe
Andrew C Jamieson
Andrew W Snowden
Carl O Pabo
Carolyn Dent
Casey C Case
Edward J Rebar
Fyodor Urnov
H Steven Zhang
Siyuan Tan
P304
P407
P577
2003-12-01T00:00:00Z