Chorismate synthase of Neurospora crassa: a flavoprotein

Chorismate synthase of Neurospora crassa: a flavoprotein

Item
http://www.wikidata.org/entity/Q28237321
The Shikimate Pathway: Early Steps in the Biosynthesis of Aromatic CompoundsCrystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiaeStudies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reactionEvidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate bindingSpectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH.Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate.Cloning and characterization of a heterologously expressed bifunctional chorismate synthase/flavin reductase from Neurospora crassa.Influence of an aggregated multienzyme system on transient time: kinetic evidence for compartmentation by an aromatic-amino-acid synthesizing complex of Neurospora crassaEscherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved.The overexpression, purification and complete amino acid sequence of chorismate synthase from Escherichia coli K12 and its comparison with the enzyme from Neurospora crassaChorismate synthase from the hyperthermophile Thermotoga maritima combines thermostability and increased rigidity with catalytic and spectral properties similar to mesophilic counterparts.Mechanism of chorismate synthase. Role of the two invariant histidine residues in the active site.Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity.Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase.Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway
P2860

Chorismate synthase of Neurospora crassa: a flavoprotein

Item
http://www.wikidata.org/entity/Q28237321
description
1974 nî lūn-bûn
@nan
1974 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1974 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1974年の論文
@ja
1974年論文
@yue
1974年論文
@zh-hant
1974年論文
@zh-hk
1974年論文
@zh-mo
1974年論文
@zh-tw
1974年论文
@wuu
name
Chorismate synthase of Neurospora crassa: a flavoprotein
@ast
Chorismate synthase of Neurospora crassa: a flavoprotein
@en
Chorismate synthase of Neurospora crassa: a flavoprotein
@nl
type
label
Chorismate synthase of Neurospora crassa: a flavoprotein
@ast
Chorismate synthase of Neurospora crassa: a flavoprotein
@en
Chorismate synthase of Neurospora crassa: a flavoprotein
@nl
prefLabel
Chorismate synthase of Neurospora crassa: a flavoprotein
@ast
Chorismate synthase of Neurospora crassa: a flavoprotein
@en
Chorismate synthase of Neurospora crassa: a flavoprotein
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Chorismate synthase of Neurospora crassa: a flavoprotein
@en
P2093
P304
P31
P356
10.1016/0003-9861(74)90276-8
P407
P433
P478
P577
P698