The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
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The public road to high-quality curated biological pathwaysMYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genesGenetic regulation of unsaturated fatty acid composition in C. elegansWeb-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's diseaseExpression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac deathcDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolismA conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domainMammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressPotential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latencyMolecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteinsRole of LXRs in control of lipogenesisMondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysisAnnexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradationRhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signalingSIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolismLuman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response elementSterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolismCharacterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteinsNutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathwayMutations in NOTCH1 cause aortic valve diseaseSRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cellsSecreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic miceCLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activityA novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein responseIdentification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating proteinStress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processingDISP3, a sterol-sensing domain-containing protein that links thyroid hormone action and cholesterol metabolismCREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P.Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adiHCF-dependent nuclear import of VP16Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transportA novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain proteinIdentification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterDimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin betaHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsFructose, insulin resistance, and metabolic dyslipidemiaNonalcoholic fatty liver disease: a comprehensive review of a growing epidemicRegulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
P2860
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P2860
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The SREBP pathway: regulation ...... ane-bound transcription factor
@ast
The SREBP pathway: regulation ...... ane-bound transcription factor
@en
The SREBP pathway: regulation ...... ane-bound transcription factor
@nl
type
label
The SREBP pathway: regulation ...... ane-bound transcription factor
@ast
The SREBP pathway: regulation ...... ane-bound transcription factor
@en
The SREBP pathway: regulation ...... ane-bound transcription factor
@nl
prefLabel
The SREBP pathway: regulation ...... ane-bound transcription factor
@ast
The SREBP pathway: regulation ...... ane-bound transcription factor
@en
The SREBP pathway: regulation ...... ane-bound transcription factor
@nl
P3181
P1433
P1476
The SREBP pathway: regulation ...... ane-bound transcription factor
@en
P2093
J L Goldstein
P304
P3181
P356
10.1016/S0092-8674(00)80213-5
P407
P577
1997-05-02T00:00:00Z