Rational biosynthetic engineering for optimization of geldanamycin analogues

Rational biosynthetic engineering for optimization of geldanamycin analogues

Item
http://www.wikidata.org/entity/Q28239092
Natalamycin A, an Ansamycin from a Termite-Associated Streptomyces sp.Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy.Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification.Broad substrate specificity of the amide synthase in S. hygroscopicus--new 20-membered macrolactones derived from geldanamycin.Identification of new geldanamycin derivatives from unexplored microbial culture extracts using a MS/MS library.In vitro reconstitution and analysis of the 6-deoxyerythronolide B synthase.Biosynthetic origin of butyrolactol A, an antifungal polyketide produced by a marine-derived Streptomyces.Protein engineering towards natural product synthesis and diversification.New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus.Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe.New, non-quinone fluorogeldanamycin derivatives strongly inhibit Hsp90.Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase.
P2860

Rational biosynthetic engineering for optimization of geldanamycin analogues

Item
http://www.wikidata.org/entity/Q28239092
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
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2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
Rational biosynthetic engineering for optimization of geldanamycin analogues
@ast
Rational biosynthetic engineering for optimization of geldanamycin analogues
@en
Rational biosynthetic engineering for optimization of geldanamycin analogues
@nl
type
label
Rational biosynthetic engineering for optimization of geldanamycin analogues
@ast
Rational biosynthetic engineering for optimization of geldanamycin analogues
@en
Rational biosynthetic engineering for optimization of geldanamycin analogues
@nl
prefLabel
Rational biosynthetic engineering for optimization of geldanamycin analogues
@ast
Rational biosynthetic engineering for optimization of geldanamycin analogues
@en
Rational biosynthetic engineering for optimization of geldanamycin analogues
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Rational biosynthetic engineering for optimization of geldanamycin analogues
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698