Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma - Wikidata - awgldk - TriplyDB

Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma

Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma

http://www.wikidata.org/entity/Q28239503

about

Role of multifaceted regulators in cancer glucose metabolism and their clinical significance An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model From Krebs to clinic: glutamine metabolism to cancer therapy.Kidney-type glutaminase (GLS1) is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis.microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo.Molecular alterations in the carcinogenesis and progression of hepatocellular carcinoma: Tumor factors and background liver factors.Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling.Pontin, a new mutant p53-binding protein, promotes gain-of-function of mutant p53.Glutamine Addiction In Gliomas.The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma.Synthesis and Characterization of Novel BMI1 Inhibitors Targeting Cellular Self-Renewal in Hepatocellular Carcinoma.The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.Glutamine Metabolism in Gliomas.Downregulation of GLS2 in glioblastoma cells is related to DNA hypermethylation but not to the p53 status.Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma.

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P2860

Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma

http://www.wikidata.org/entity/Q28239503

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@ast

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@en

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

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type

label

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@ast

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@en

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@nl

prefLabel

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@ast

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@en

Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

@nl

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Glutaminase 2 negatively regul ...... human hepatocellular carcinoma

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Cen Zhang

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Juan Liu

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Ken H Young

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Meihua Lin

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Wei Zhu

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Wenwei Hu

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Xuehui Hong

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Yingjian Liang

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Zhaohui Feng

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P2860

Global cancer statistics

Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

The first 30 years of p53: growing ever more complex

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

p53 regulates maternal reproduction through LIF

Blinded by the Light: The Growing Complexity of p53

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

Cancer epigenomics: DNA methylomes and histone-modification maps

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