Strategy and success for the directed evolution of enzymes
about
Targeted metagenomics unveils the molecular basis for adaptive evolution of enzymes to their environmentDirected evolution combined with synthetic biology strategies expedite semi-rational engineering of genes and genomesMicrobial enzymes: tools for biotechnological processesA review of metabolic and enzymatic engineering strategies for designing and optimizing performance of microbial cell factoriesLibrary methods for structural biology of challenging proteins and their complexesDirected evolution: tailoring biocatalysts for industrial applicationsDiscovery and Characterization of a Thermostable and Highly Halotolerant GH5 Cellulase from an Icelandic Hot Spring IsolateCatalytic DNA with phosphatase activitySingle-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encodedOligomerization triggered by foldon: a simple method to enhance the catalytic efficiency of lichenase and xylanase.An automated flow for directed evolution based on detection of promiscuous scaffolds using spatial and electrostatic properties of catalytic residues.Use of nonionic surfactants for improvement of terpene production in Saccharomyces cerevisiae.Enhancing RGI lyase thermostability by targeted single point mutations.OptZyme: computational enzyme redesign using transition state analoguesDirected evolution by using iterative saturation mutagenesis based on multiresidue sites.Mutagenic Organized Recombination Process by Homologous IN vivo Grouping (MORPHING) for directed enzyme evolution.Directed Evolution: Past, Present and Future.Directed Evolution and Mutant Characterization of Nitrilase from Rhodococcus rhodochrous tg1-A6.An in vitro compartmentalization-based method for the selection of bond-forming enzymes from large librariesSaccharomyces cerevisiae in directed evolution: An efficient tool to improve enzymes.Engineering and Directed Evolution of DNA Methyltransferases.Evolving Methanococcoides burtonii archaeal Rubisco for improved photosynthesis and plant growth.EstDZ3: A New Esterolytic Enzyme Exhibiting Remarkable Thermostability.Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.Catalytic, mild, and selective oxyfunctionalization of linear alkanes: current challenges.Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro.Modulating protein stability - directed evolution strategies for improved protein function.Dynamics and constraints of enzyme evolution.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Directed evolution 2.0: improving and deciphering enzyme properties.Protein engineering and de novo designing of a biocatalyst.Correlated positions in protein evolution and engineering.Molecular mechanical properties of short-sequence peptide enzyme mimics.Conscious coupling: The challenges and opportunities of cascading enzymatic microreactors.Discovery of human-like L-asparaginases with potential clinical use by directed evolution.Random mutagenesis by error-prone pol plasmid replication in Escherichia coli.Improving kinetic or thermodynamic stability of an azoreductase by directed evolution.Two strategies to engineer flexible loops for improved enzyme thermostability.Rational stabilization of complex proteins: a divide and combine approach.Rational mutagenesis by engineering disulphide bonds improves Kluyveromyces lactis beta-galactosidase for high-temperature industrial applications.
P2860
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P2860
Strategy and success for the directed evolution of enzymes
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Strategy and success for the directed evolution of enzymes
@ast
Strategy and success for the directed evolution of enzymes
@en
Strategy and success for the directed evolution of enzymes
@nl
type
label
Strategy and success for the directed evolution of enzymes
@ast
Strategy and success for the directed evolution of enzymes
@en
Strategy and success for the directed evolution of enzymes
@nl
prefLabel
Strategy and success for the directed evolution of enzymes
@ast
Strategy and success for the directed evolution of enzymes
@en
Strategy and success for the directed evolution of enzymes
@nl
P3181
P1476
Strategy and success for the directed evolution of enzymes
@en
P2093
Paul A Dalby
P304
P3181
P356
10.1016/J.SBI.2011.05.003
P407
P577
2011-08-01T00:00:00Z