about
Gene regulation, alternative splicing, and posttranslational modification of troponin subunits in cardiac development and adaptation: a focused reviewCell biology of sarcomeric protein engineering: disease modeling and therapeutic potentialCalcium induced regulation of skeletal troponin--computational insights from molecular dynamics simulationsStructure of the complex of a mitotic kinesin with its calcium binding regulatorSolution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (-)-Epigallocatechin 3-GallateSolution Structure of the Apo C-Terminal Domain of the Lethocerus F1 Troponin C IsoformSolution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: The basis of W7 as an inhibitor of cardiac muscle contractionA structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complexStructural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein MiroCardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy PhenotypeProtein Structure-Function Relationship at Work: Learning from Myopathy Mutations of the Slow Skeletal Muscle Isoform of Troponin TThe Importance of Intrinsically Disordered Segments of Cardiac Troponin in Modulating Function by Phosphorylation and Disease-Causing MutationsCalcium-regulated conformational change in the C-terminal end segment of troponin I and its binding to tropomyosinRegulatory domain of troponin moves dynamically during activation of cardiac muscleTargeting the sarcomere to correct muscle functionSelective deletion of the NH2-terminal variable region of cardiac troponin T in ischemia reperfusion by myofibril-associated mu-calpain cleavageThe C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filamentsStructural dynamics of troponin I during Ca2+-activation of cardiac thin filaments: a multi-site Förster resonance energy transfer studyLocalization of the two tropomyosin-binding sites of troponin TDefining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complexTroponin T core structure and the regulatory NH2-terminal variable regionTroponin T isoforms and posttranscriptional modifications: Evolution, regulation and functionStructure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugsIntegrative structural modelling of the cardiac thin filament: energetics at the interface and conservation patterns reveal a spotlight on period 2 of tropomyosinTNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships.Allosteric Transmission along a Loosely Structured Backbone Allows a Cardiac Troponin C Mutant to Function with Only One Ca2+ Ion.Ca2+ -induced tropomyosin movement in scallop striated muscle thin filamentsX-ray diffraction evidence for myosin-troponin connections and tropomyosin movement during stretch activation of insect flight musclePathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations.A model of calcium activation of the cardiac thin filamentKinetics of cardiac thin-filament activation probed by fluorescence polarization of rhodamine-labeled troponin C in skinned guinea pig trabeculaeCa2+-dependent photocrosslinking of tropomyosin residue 146 to residues 157-163 in the C-terminal domain of troponin I in reconstituted skeletal muscle thin filaments.A novel approach to the structural analysis of partially decorated actin based filaments.Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation.Troponin regulatory function and dynamics revealed by H/D exchange-mass spectrometry.Close proximity of myosin loop 3 to troponin determined by triangulation of resonance energy transfer distance measurements.Ca(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filMolecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residuesThe mitochondrial Ras-related GTPase Miro: views from inside and outside the metazoan kingdom.Cooperative [Ca²+]-dependent regulation of the rate of myosin binding to actin: solution data and the tropomyosin chain model.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Ca(2+)-regulated structural changes in troponin
@ast
Ca(2+)-regulated structural changes in troponin
@en
Ca(2+)-regulated structural changes in troponin
@nl
type
label
Ca(2+)-regulated structural changes in troponin
@ast
Ca(2+)-regulated structural changes in troponin
@en
Ca(2+)-regulated structural changes in troponin
@nl
prefLabel
Ca(2+)-regulated structural changes in troponin
@ast
Ca(2+)-regulated structural changes in troponin
@en
Ca(2+)-regulated structural changes in troponin
@nl
P2093
P2860
P3181
P356
P1476
Ca(2+)-regulated structural changes in troponin
@en
P2093
Christina Karatzaferi
Deborah B Stone
Galina G Malanina
Maia V Vinogradova
Robert A Mendelson
Robert J Fletterick
Roger Cooke
P2860
P304
P3181
P356
10.1073/PNAS.0408882102
P407
P577
2005-04-05T00:00:00Z