Impaired "outside-in" integrin alphaIIbbeta3 signaling and thrombus stability in TSSC6-deficient mice
about
The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expressionIdentification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomainsTetraspanins as therapeutic targets in hematological malignancy: a concise reviewDisabled-2 is required for efficient hemostasis and platelet activation by thrombin in miceRGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.Role for ADAP in shear flow-induced platelet mechanotransduction.CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.Lateral organization of membrane proteins: tetraspanins spin their web.Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolismEvaluation of targeting c-Src by the RGT-containing peptide as a novel antithrombotic strategy.Targeting of tetraspanin proteins--potential benefits and strategiesDeficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal functionTetraspanins and vascular functions.Tetraspanin microdomains: fine-tuning platelet function.The effects of arterial flow on platelet activation, thrombus growth, and stabilization.Preventive Role of Tetraspanin CD9 in Systemic Inflammation of Chronic Obstructive Pulmonary Disease.Integrin αIIbβ3 outside-in signaling.Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.CEACAM2 positively regulates integrin αIIbβ3-mediated platelet functions.Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration.Platelet Integrins in Tumor Metastasis: Do They Represent a Therapeutic Target?Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation.Reduced body weight in male Tspan8-deficient mice.CEACAM1 regulates integrin αIIbβ3-mediated functions in platelets.
P2860
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P2860
Impaired "outside-in" integrin alphaIIbbeta3 signaling and thrombus stability in TSSC6-deficient mice
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@ast
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@en
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@nl
type
label
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@ast
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@en
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@nl
prefLabel
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@ast
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@en
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@nl
P2093
P1433
P1476
Impaired "outside-in" integrin ...... bility in TSSC6-deficient mice
@en
P2093
Denise E Jackson
Janet L Wee
Lai-Man Lau
Lorraine M Robb
Mark D Wright
Matt W Goschnick
P Mark Hogarth
Yong S Liu
P304
P356
10.1182/BLOOD-2006-02-004267
P407
P577
2006-05-23T00:00:00Z