Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization
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Defective calcium inactivation causes long QT in obese insulin-resistant ratCaveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channelsCaV1.2 signaling complexes in the heartL-type calcium channel targeting and local signalling in cardiac myocytesStructure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channelsGain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromesDirect interaction of CaVβ with actin up-regulates L-type calcium currents in HL-1 cardiomyocytesNew short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channelThe ß subunit of voltage-gated Ca2+ channelsThe calcium channel beta2 (CACNB2) subunit repertoire in teleosts.Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndromeIncreased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failureDiversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling.Regulation of high-voltage-activated Ca(2+) channel function, trafficking, and membrane stability by auxiliary subunits.Oligomerization of Cavbeta subunits is an essential correlate of Ca2+ channel activity.Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.Cardiac L-type calcium channel (Cav1.2) associates with gamma subunits.The Ca2+ channel beta4c subunit interacts with heterochromatin protein 1 via a PXVXL binding motif.Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.Small GTPase Rab11b regulates degradation of surface membrane L-type Cav1.2 channelsGene splicing of an invertebrate beta subunit (LCavβ) in the N-terminal and HOOK domains and its regulation of LCav1 and LCav2 calcium channels.Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function.Rational strategy to stop arrhythmias: Early afterdepolarizations and L-type Ca2+ current.Intramolecular ex vivo Fluorescence Resonance Energy Transfer (FRET) of Dihydropyridine Receptor (DHPR) β1a Subunit Reveals Conformational Change Induced by RYR1 in Mouse Skeletal MyotubesDifferent subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytesLoss-of-function mutations in the KCNJ8-encoded Kir6.1 K(ATP) channel and sudden infant death syndrome.Genetic modifiers to the PLN L39X mutation in a patient with DCM and sustained ventricular tachycardia?Cardiac system bioenergetics: metabolic basis of the Frank-Starling law.Vascular calcium channels and high blood pressure: pathophysiology and therapeutic implications.A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits.Cardiac sulfonylurea receptor short form-based channels confer a glibenclamide-insensitive KATP activityNew Determinant for the CaVbeta2 subunit modulation of the CaV1.2 calcium channelDisrupting calcium channel expression to lower blood pressure: new targeting of a well-known channelConnexin 43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium.Small GTPase determinants for the Golgi processing and plasmalemmal expression of human ether-a-go-go related (hERG) K+ channels.Design of mutant beta2 subunits as decoy molecules to reduce the expression of functional Ca2+ channels in cardiac cells.Beta-adrenergic stimulation of L-type Ca2+ channels in cardiac myocytes requires the distal carboxyl terminus of alpha1C but not serine 1928Cooperative regulation of Ca(v)1.2 channels by intracellular Mg(2+), the proximal C-terminal EF-hand, and the distal C-terminal domain.Supramolecular assemblies and localized regulation of voltage-gated ion channels.
P2860
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P2860
Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Molecular heterogeneity of cal ...... ntial subcellular localization
@ast
Molecular heterogeneity of cal ...... ntial subcellular localization
@en
Molecular heterogeneity of cal ...... ntial subcellular localization
@nl
type
label
Molecular heterogeneity of cal ...... ntial subcellular localization
@ast
Molecular heterogeneity of cal ...... ntial subcellular localization
@en
Molecular heterogeneity of cal ...... ntial subcellular localization
@nl
prefLabel
Molecular heterogeneity of cal ...... ntial subcellular localization
@ast
Molecular heterogeneity of cal ...... ntial subcellular localization
@en
Molecular heterogeneity of cal ...... ntial subcellular localization
@nl
P2093
P1476
Molecular heterogeneity of cal ...... ntial subcellular localization
@en
P2093
Anne Marie R Yunker
Craig T January
Jason D Foell
Jeffrey W Walker
Maureen W McEnery
Ravi C Balijepalli
Seth L Robia
P304
P356
10.1152/PHYSIOLGENOMICS.00207.2003
P407
P577
2004-04-13T00:00:00Z