The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex
about
Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humansMutations in the CYP11B1 gene causing congenital adrenal hyperplasia and hypertension cluster in exons 6, 7, and 8Structural insights into aldosterone synthase substrate specificity and targeted inhibitionRegulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factorThe human steroid hydroxylases CYP1B1 and CYP11B2Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiencyGlucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersA novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22)Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein AssembliesCYP11B1 mutations causing non-classic adrenal hyperplasia due to 11 beta-hydroxylase deficiencyP450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activitiesStructure of an ovine CYP11B1 gene.Functional and expression analysis of ovine steroid 11 beta-hydroxylase (cytochrome P450 11 beta).Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.Familial hyperaldosteronism.RAAS and adrenergic genes in heart failure: Function, predisposition and survival implicationsAdrenocortical causes of hypertensionIdentification of SPRED2 (sprouty-related protein with EVH1 domain 2) as a negative regulator of the hypothalamic-pituitary-adrenal axis.A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale.Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree.Alteration in accumulated aldosterone synthesis as a result of N-terminal cleavage of aldosterone synthaseThe nature of essential hypertension: still a cognitive maze.A role for the NGFI-B family in adrenal zonation and adrenocortical disease.Antiaging Gene Klotho Regulates Adrenal CYP11B2 Expression and Aldosterone SynthesisAnalysis of renin-angiotensin aldosterone system gene polymorphisms in Malaysian essential hypertensive and type 2 diabetic subjects.Corticosterone Methyl Oxidase Deficiency Type 1 with Normokalemia in an Infant.Development of monoclonal antibodies against human CYP11B1 and CYP11B2.Impact of polymorphisms in the renin-angiotensin-aldosterone system on hypertrophic cardiomyopathy.11β-hydroxyandrostenedione returns to the steroid arena: biosynthesis, metabolism and function.Dissecting the molecular pathways of primary aldosteronism.The potential of targeting CYP11B.Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism.Regulation of adrenal aldosterone production by serine protease prostasin.Association of aldosterone synthase (CYP11B2) -344 T/C polymorphism with diabetic nephropathy: A meta-analysis.Involvement of an AP-1 complex in zone-specific expression of the CYP11B1 gene in the rat adrenal cortex.Regulation of human CYP11B2 and CYP11B1: comparing the role of the common CRE/Ad1 element.Congenital hypoaldosteronism: the Visser-Cost syndrome revisited.Does primary salt wasting occur in 11-beta-hydroxylase deficiency?Calcium regulates human CYP11B2 transcription.
P2860
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P2860
The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex
description
1991 nî lūn-bûn
@nan
1991 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@ast
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@en
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@nl
type
label
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@ast
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@en
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@nl
prefLabel
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@ast
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@en
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@nl
P2093
P3181
P356
P1476
The product of the CYP11B2 gen ...... is in the human adrenal cortex
@en
P2093
J L Nadler
K M Curnow
M T Tusie-Luna
R Natarajan
P304
P3181
P356
10.1210/MEND-5-10-1513
P407
P577
1991-10-01T00:00:00Z