The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif
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Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) ProteinsCa2+ regulation of ion transport in the Na+/Ca2+ exchangerThe second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis.Structure and Functional Analysis of a Ca2+ Sensor Mutant of the Na+/Ca2+ ExchangerCa2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanismStructural Basis of the Ca2+ Inhibitory Mechanism of Drosophila Na+/Ca2+ Exchanger CALX and Its Modification by Alternative SplicingStructural basis for alternating access of a eukaryotic calcium/proton exchangerNMR structure note: solution structure of Ca²⁺ binding domain 2B of the third isoform of the Na⁺/Ca²⁺ exchangerStructural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchangerNa+/Ca2+ exchange and Na+/K+-ATPase in the heartCrystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions.Structure-based dynamic arrays in regulatory domains of sodium-calcium exchanger (NCX) isoforms.Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains.A common Ca2+-driven interdomain module governs eukaryotic NCX regulationTransmembrane segment packing of the Na(+)/Ca(2+) exchanger investigated with chemical cross-linkersCa2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers.The plasma membrane Ca²+ ATPase and the plasma membrane sodium calcium exchanger cooperate in the regulation of cell calcium.Ca2+ binding alters the interdomain flexibility between the two cytoplasmic calcium-binding domains in the Na+/Ca2+ exchangerProton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger.Getting a grip on calcium regulation.Direct Loading of the purified endogenous inhibitor into the cytoplasm of patched cardiomyocytes blocks the ion currents and calcium transport through the NCX1 protein.Structural arrangement of the intracellular Ca2+ binding domains of the cardiac Na+/Ca2+ exchanger (NCX1.1): effects of Ca2+ binding.Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman.Structural basis for Ca2+ regulation in the Na+/Ca2+ exchanger.The regulation of the Na/Ca exchanger and plasmalemmal Ca2+ ATPase by other proteins.Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart.Structure and dynamics of Ca2+-binding domain 1 of the Na+/Ca2+ exchanger in the presence and in the absence of Ca2+beta-adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cellsRoles of two Ca2+-binding domains in regulation of the cardiac Na+-Ca2+ exchanger.Structural and dynamic aspects of Ca2+ and Mg2+ binding of the regulatory domains of the Na+/Ca2+ exchanger.20 years from NCX purification and cloning: milestones.Dual control of cardiac Na+ Ca2+ exchange by PIP(2): electrophysiological analysis of direct and indirect mechanisms.How a helix imposes palmitoylation of a membrane protein: What one can learn from NCX.Crystallization and preliminary X-ray crystallographic analysis of Ca2+-free primary Ca2+-sensor of Na+/Ca2+ exchanger.Population shift underlies Ca2+-induced regulatory transitions in the sodium-calcium exchanger (NCX).Essential role of the CBD1-CBD2 linker in slow dissociation of Ca2+ from the regulatory two-domain tandem of NCX1.Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange.Structure-dynamic determinants governing a mode of regulatory response and propagation of allosteric signal in splice variants of Na+/Ca2+ exchange (NCX) proteins.Characterization of zebrafish (Danio rerio) NCX4: a novel NCX with distinct electrophysiological properties.Molecular determinants of pH regulation in the cardiac Na+-Ca2+ exchanger.
P2860
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P2860
The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The crystal structure of the p ...... als a novel Ca2+ binding motif
@ast
The crystal structure of the p ...... als a novel Ca2+ binding motif
@en
The crystal structure of the p ...... als a novel Ca2+ binding motif
@nl
type
label
The crystal structure of the p ...... als a novel Ca2+ binding motif
@ast
The crystal structure of the p ...... als a novel Ca2+ binding motif
@en
The crystal structure of the p ...... als a novel Ca2+ binding motif
@nl
prefLabel
The crystal structure of the p ...... als a novel Ca2+ binding motif
@ast
The crystal structure of the p ...... als a novel Ca2+ binding motif
@en
The crystal structure of the p ...... als a novel Ca2+ binding motif
@nl
P2093
P356
P1476
The crystal structure of the p ...... als a novel Ca2+ binding motif
@en
P2093
Debora A Nicoll
Duilio Cascio
Jeff Abramson
Kenneth D Philipson
Michael R Sawaya
Seunghyug Kwon
P304
P356
10.1074/JBC.C600117200
P407
P577
2006-08-04T00:00:00Z