From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
about
ZNF9 activation of IRES-mediated translation of the human ODC mRNA is decreased in myotonic dystrophy type 2microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorderMultiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95Normal development of brain circuitsFragile X syndrome: loss of local mRNA regulation alters synaptic development and functionWhat can we learn about autism from studying fragile X syndrome?Advances in the treatment of fragile X syndromeFragile x syndromeA direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.mTOR signaling: at the crossroads of plasticity, memory and diseaseThe PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Advances in the Understanding of the Gabaergic Neurobiology of FMR1 Expanded Alleles Leading to Targeted Treatments for Fragile X Spectrum DisorderBehavioral phenotypes of genetic mouse models of autism.Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of AutismAbnormal kalirin signaling in neuropsychiatric disorders.Learning and behavioral deficits associated with the absence of the fragile X mental retardation protein: what a fly and mouse model can teach us.Dendritic spine dysgenesis in autism related disordersThe unstable repeats--three evolving faces of neurological diseaseFunctional magnetic resonance imaging in awake transgenic fragile X rats: evidence of dysregulation in reward processing in the mesolimbic/habenular neural circuitCommon mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disordersFragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virusA new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stabilityRoles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalizationDSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesisRegulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132Pten regulates neuronal arborization and social interaction in mice.Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in ZebrafishThe Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptorsDendritic LSm1/CBP80-mRNPs mark the early steps of transport commitment and translational controlUncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndromeNovel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticityDendritic spine pathology in neuropsychiatric disordersProgress toward therapeutic potential for AFQ056 in Fragile X syndrome.Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model.Gestational and early postnatal hypothyroidism alters VGluT1 and VGAT bouton distribution in the neocortex and hippocampus, and behavior in rats.Ras and Rap signaling in synaptic plasticity and mental disorders.Genome-wide screen reveals APC-associated RNAs enriched in cell protrusionsRas signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome.Investigating mechanisms underlying neurodevelopmental phenotypes of autistic and intellectual disability disorders: a perspective.Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.
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P2860
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@ast
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@en
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@nl
type
label
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@ast
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@en
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@nl
prefLabel
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@ast
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@en
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@nl
P2860
P3181
P356
P1476
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
@en
P2093
William T Greenough
P2860
P2888
P304
P3181
P356
10.1038/NRN1667
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P577
2005-05-01T00:00:00Z
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P6179
1028385483